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GuoliangLi-HZAU / BatMeth2

BS-seq analysis pipeline
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BatMeth2 calmeth calculates slowly. #44

Closed aijigekoukou-shen closed 10 months ago

aijigekoukou-shen commented 1 year ago

Dear Prof. Li,

I hope this message finds you well. I am writing to express my gratitude for providing the methylation analysis software, which has been incredibly helpful to me in my recent projects.

However, I encountered an issue while using BatMeth2 calmeth for calculating methylation sites at the genome-wide level. I generated the necessary bam files using bismark, but the calmeth analysis has been running for the past two days without completion. I consulted the available documentation but was unable to find any parameters that could potentially speed up the analysis.

I would greatly appreciate any guidance or assistance you could provide to help resolve this issue.

Thank you once again for your support.

Best regards, Shen

aijigekoukou-shen commented 10 months ago

Unsorted bam files can cause slowdowns.