Roadrunner does not correctly handle estimated noise parameters

ICB-DCM / pyPESTO

python Parameter EStimation TOolbox

https://pypesto.readthedocs.io

BSD 3-Clause "New" or "Revised" License

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Roadrunner does not correctly handle estimated noise parameters #1441

Open PaulJonasJost opened 1 month ago

PaulJonasJost commented 1 month ago

When using the PEtab problem from Boehm, roadrunnerObjective has a different output to amici, but the same simulation. The Value is getting equal when fixing the noise parameters. Probably due to how the objective function collects the noise values from roadrunner.

PaulJonasJost commented 1 week ago

fixed in #1442 as a side effect.