IKIM-Essen / uncovar

Transparent and robust SARS-CoV-2 variant calling and lineage assignment with comprehensive reporting.
https://ikim-essen.github.io/uncovar
BSD 2-Clause "Simplified" License
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fix: use homopolymer-pair-HMM-mode of Varlociraptor in case of nanopore reads #587

Closed johanneskoester closed 1 year ago

johanneskoester commented 1 year ago

nanopore suffers from homopolymer errors. Varlociraptor can deal with them by having additional states in its pairHMM used for realignment of reads against considered alleles. This mode has to be explicitly activated whenever we process a nanopore sample.

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