Immunotools / igscout

A tool for de novo inference of D and J genes using Rep-seq data; analysis of CDR3 diversity; finding VDDJ recombination
GNU General Public License v3.0
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igscout

IgScout is a tool for de novo inference of D and J genes using Rep-seq data; analysis of CDR3 diversity; finding VDDJ recombination.

Please note that this is a very first version of the tool and its usability will be improved in the future. Any suggestions for improvements are welcomed!

Usage:

python igscout.py -i input_cdr3s.fasta -k kmer_size -o output_dir

python tandem_cdr3_finder.py d_genes.fasta input_cdr3s.fasta output_dir

Dependencies:

Biopython

Matplotlib

seaborn

NumPy