This platform provides tools and workflows for early risk assessment using toxicogenomics based on publically available data sources or other data sets that have been released in support of this platform. It is expected that this platform will accelerate the development of the supporting science and increase adoption of new risks assessment tools by the broader research community.
Currently this platform is in the early prototype phase to establish secure collaboration tools for participating organizations and to define the conceptual architecture and framework that leverages and/or integrates with other efforts in toxicogenomics. The first working implementation of this platform delivers a full end-to-end workflow from data to visualizations with to-be-defined research methods based on the best practices of the Sponsor(s).
J J Sutherland, Y W Webster, J A Willy, G H Searfoss, K M Goldstein, A R Irizarry, D G Hall, and J L Stevens, 'Toxicogenomic module associations with pathogenesis (TXG-MAP): A network based approach to understanding drug toxicity', The Pharmacogenomics Journal, Advance Online Publication
Jeffrey J Sutherland James L Stevens Kamin Johnson Navin Elango Yue W Webster Bradley J Mills Daniel H Robertson, 'A novel open access web portal for integrating mechanistic and toxicogenomic study results', Toxicological Sciences, Advance Online Publication
Visit our current deployment here: link
If you signup you will recieve an email notifying you of granted access.
Link to deployment documentation
The tests run from runner.py and will go through in testing each pipeline including email, rabbitmq, celery, our data processes, and your R installation
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See also the list of contributors who participated in this project.
Contact Brad Mills at bmills(at)indianabiosciences(dot)org