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KechrisLab / multiMiR

Development repository for the multiMiR database's R API
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What the functional column does mean please #42

Open beginner984 opened 2 years ago

beginner984 commented 2 years ago

Hello

I have put a lot of miRNAs in your software and I obtained a list of validated target genes for them by

example1 <- get_multimir(mirna = c("hsa-mir-1469",
+ "hsa-mir-12128p"), summary = TRUE)

In supported_type column of the results I see like this

Screenshot 2021-10-04 at 10 30 58

I could not find what each one does mean, likeMIT, NEGATIVE, POSITIVE, WEAK, ETC

Could you please help me to get some intuition and ultimately I could refine my results.

Thank you so much in advance

smahaffey commented 2 years ago

@beginner984 I'm so sorry for the very delayed response. I can not immediately find a description of those values. I will forward this question on to the team and see if anyone had some other documentation or knows what it is.

smahaffey commented 2 years ago

@beginner984 Again sorry for the delay. These values seem to be from mirTarbase and not mirecords. mirTarbase also seems to have changed URLs to https://mirtarbase.cuhk.edu.cn/~miRTarBase/miRTarBase_2022/php/index.php

I believe this simply matches the classification of the support strong/weak based on the type of experiment that supports this interaction as can be seen in their current summary table(attached image) when browsing interactions on the current website.

image