MOZI-AI / annotation-service

The gene annotation service maps human gene symbols to their biological context as represented in an OpenCog Knowledge Hypergraph
https://mozi.ai
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covid19 data filtering inconsistencies #50

Open mjsduncan opened 4 years ago

mjsduncan commented 4 years ago

input annotation request was SARS-CoV-2 "M" gene with reactome pathway and biogrid with cross-annotation. in the "gene only" output, the whole graph is considered "biogrid-interaction-annotation" under "annotation" filtering, the pathway and GO filters have no effect (GO was not requested, separate issue will be posted). M gene only filters 2020-05-05

when proteins are included in the input request, filtering out "gene-pathway-annotation" removes the SARS-CoV-2 M gene and it's interactions, which should all be biogrid interactions. if "M" is part of a pathway it should be the "pathway" defined as the set of all SARS2 genes. M is pathway 2020-05-05

filtering out "biogrid-interaction-annotation" removes expressed proteins and their "inferred_interactions" but leaves the actual biogrid "interacts_with" links visible. biogrid is only proteins 2020-05-05

also note that SARS2 "M" gene doesn't have translated protein node (this might be a data import error) sars2 M with proteins 2020-05-05