Nextomics / NextDenovo

Fast and accurate de novo assembler for long reads
GNU General Public License v3.0
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For low base quality of sequences #202

Open YouxinZhao opened 3 months ago

YouxinZhao commented 3 months ago

I am using nextDenovo to assamble genome with ONT reads. The long reads usually have low base quality. And I wonder how these sequences will be handled in Nextdenove? Discard or correct? image

moold commented 3 months ago

Nextdenovo discards reads with low mapping coverage or clips regions of low mapping coverage in reads, and low-quality reads generally have lower mapping coverage.