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Publications of all kind based on the Open Systems Pharmacology Suite
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Physiologically-based pharmacokinetic modeling and dosing optimization of cefotaxime in preterm and term neonates
#557
Yuri05
opened
6 months ago
0
A Comprehensive Physiologically Based Pharmacokinetic Model of Nadolol in Adults with Renal Disease and Pediatrics with Supraventricular Tachycardia
#556
AndreDlm
opened
7 months ago
0
A deep neural network: mechanistic hybrid model to predict pharmacokinetics in rat
#555
AndreDlm
opened
8 months ago
0
Personalized Chronomodulated 5-Fluorouracil Treatment: A Physiologically-Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy
#554
AndreDlm
opened
8 months ago
0
Morphine concentrations in fatalities after palliative treatment of acute burn injury
#553
JanSchlender
opened
8 months ago
0
Physiologically based pharmacokinetic modeling to predict maternal pharmacokinetics and fetal carbamazepine exposure during pregnancy
#552
tobiasK2001
opened
8 months ago
0
Physiologically Based Pharmacokinetic Modeling in Neonates: Current Status and Future Perspectives
#551
JanSchlender
closed
7 months ago
1
Metformin-Cimetidine Drug Interaction and Risk of Lactic Acidosis in Renal Failure: A Pharmacovigilance-Pharmacokinetic Appraisal
#550
JanSchlender
opened
8 months ago
0
Prediction of drug–drug interactions between roflumilast and CYP3A4/1A2 perpetrators using a physiologically-based pharmacokinetic (PBPK) approach
#549
JanSchlender
opened
8 months ago
0
In Silico and In Vivo Pharmacokinetic Evaluation of 84-B10, a Novel Drug Candidate against Acute Kidney Injury and Chronic Kidney Disease
#548
AndreDlm
opened
8 months ago
0
Physiologically Based Pharmacokinetic Modeling of Ritonavir-Oxycodone Drug Interactions and Its Implication for Dosing Strategy
#547
AndreDlm
opened
8 months ago
0
Novel phenylthiazoles with a tert-butyl moiety: promising antimicrobial activity against multidrug-resistant pathogens with enhanced ADME properties
#546
Yuri05
opened
9 months ago
0
Maximum likelihood estimation of renal transporter ontogeny profiles for pediatric PBPK modeling
#545
Yuri05
opened
9 months ago
0
Reproductive toxicity in birds predicted by physiologically-based kinetics and bioenergetics modelling
#544
Yuri05
opened
9 months ago
0
Prediction of trough concentration and ALK occupancy in plasma and cerebrospinal fluid using physiologically based pharmacokinetic modeling of crizotinib, alectinib, and lorlatinib
#543
Yuri05
opened
9 months ago
0
Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from two Clinical DDI Studies and PBPK Modeling
#542
Yuri05
opened
9 months ago
0
Physiologically based pharmacokinetic modeling of candesartan to predict the exposure in hepatic and renal impairment and elderly populations
#541
Yuri05
opened
9 months ago
0
Physiologically based pharmacokinetic (PBPK) modeling of pitavastatin in relation to SLCO1B1 genetic polymorphism
#540
Yuri05
opened
9 months ago
0
Physiologically Based Pharmacokinetic Modeling in Neonates: Current Status and Future Perspectives
#539
AndreDlm
opened
9 months ago
0
A Physiologically Based Pharmacokinetic Model to Predict Systemic Ondansetron Concentration in Liver Cirrhosis Patients
#538
AndreDlm
opened
9 months ago
0
PBPK/PD Modeling of Nifedipine for Precision Medicine in Pregnant Women: Enhancing Clinical Decision-Making for Optimal Drug Therapy
#537
AndreDlm
opened
10 months ago
0
A new publication using the OSP software
#536
AndreDlm
closed
10 months ago
0
Prediction of pediatric dose of tirzepatide from the reference adult dose using physiologically based pharmacokinetic modelling
#535
AndreDlm
opened
10 months ago
0
Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice
#534
AndreDlm
opened
10 months ago
0
Prediction of CYP down regulation after tusamitamab ravtansine administration (a DM4-conjugate), based on an in-vitro-in-vivo extrapolation approach
#533
AndreDlm
opened
10 months ago
0
Comparison of monoclonal antibody disposition predictions using different physiologically based pharmacokinetic modelling platforms
#532
AndreDlm
opened
10 months ago
0
Development of a Generic Fetal Physiologically Based Pharmacokinetic Model and Prediction of Human Maternal and Fetal Organ Concentrations of Cefuroxime
#531
AndreDlm
opened
10 months ago
1
Prediction of Human Pharmacokinetics From Chemical Structure: Combining Mechanistic Modeling with Machine Learning
#530
AndreDlm
opened
10 months ago
0
Physiologically-based pharmacokinetic modeling of nilotinib for drug-drug interactions, pediatric patients, and pregnancy and lactation
#529
AndreDlm
opened
11 months ago
0
Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition
#528
AndreDlm
opened
11 months ago
0
Paradigm Shift in Research Focus: Computational Softwares in Cancer Biology
#527
AndreDlm
opened
11 months ago
0
In Vitro Dissolution and in Silico Modeling Shortcuts in Bioequivalence Testing
#526
AndreDlm
opened
11 months ago
0
Physiologically Based Modeling Approach to Predict Dopamine D2 Receptor Occupancy of Antipsychotics in Brain: Translation From Rat to Human
#525
AndreDlm
opened
11 months ago
0
Physiologically based pharmacokinetic model combined with reverse dose method to study the nephrotoxic tolerance dose of tacrolimus
#524
AndreDlm
opened
11 months ago
0
Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network
#523
AndreDlm
opened
11 months ago
0
Reproducibility of Quantitative Systems Pharmacology Models: Current Challenges and Future Opportunities
#522
AndreDlm
opened
11 months ago
0
Saliva versus Plasma Therapeutic Drug Monitoring of Pregabalin in Jordanian Patients
#521
AndreDlm
opened
11 months ago
0
Prediction of ROS1 and TRKA/B/C occupancy in plasma and cerebrospinal fluid for entrectinib alone and in DDIs using physiologically based pharmacokinetic (PBPK) modeling approach
#520
JanSchlender
opened
11 months ago
0
A physiologically-based pharmacokinetic model for predicting doxorubicin disposition in multiple tissue levels and quantitative toxicity assessment
#519
AndreDlm
opened
11 months ago
0
In vitro-in vivo Simulation Studies On Capecitabine Loaded Niosomes Intended for Brain Targeting
#518
AndreDlm
opened
11 months ago
0
Physiologically-based pharmacokinetic modeling for optimal dosage prediction of olaparib when co-administered with CYP3A4 modulators and in patients with hepatic/renal impairment
#517
JanSchlender
opened
11 months ago
0
Physiologically-based pharmacokinetic model to predict doxorubicin and paclitaxel exposure in infants through breast milk
#516
AndreDlm
opened
11 months ago
0
Integration of artificial neural network and physiologically based biopharmaceutic models in the development of sustained-release formulations
#515
AndreDlm
opened
11 months ago
0
Applied Physiologically Based Pharmacokinetic Modeling to assess UGT-mediated Drug-Drug Interactions for Vericiguat
#514
AndreDlm
opened
11 months ago
0
Translation of Monoclonal Antibodies Pharmacokinetics from Animal to Human Using Physiologically Based Modeling in Open Systems Pharmacology (OSP) Suite: A Retrospective Analysis of Bevacizumab
#513
JanSchlender
opened
1 year ago
0
Physiologically based pharmacokinetic modelling of anti-tumour necrosis factor for IBD patients to predict the withdrawal time in pregnancy and vaccine time in infants
#512
JanSchlender
opened
1 year ago
0
Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration
#511
Yuri05
opened
1 year ago
0
Evaluating the Pharmacokinetics of Fentanyl in the Brain Extracellular Fluid, Saliva, Urine, and Plasma of Newborns from Transplacental Exposure from Parturient Mothers Dosed with Epidural Fentanyl Utilizing PBPK Modeling
#510
Yuri05
opened
1 year ago
0
Physiologically Based Pharmacokinetic Model To Predict Metoprolol Disposition in Healthy and Disease Populations
#509
AndreDlm
opened
1 year ago
0
Pharmacokinetics during therapeutic hypothermia in neonates: from pathophysiology to translational knowledge and physiologically-based pharmacokinetic (PBPK) modeling
#508
JanSchlender
opened
1 year ago
0
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