An R package with tools for analysing, managing and visualising co-methylation data. Loosely speaking, co-methylation is the correlation structure of DNA methylation.
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Write function to compute Landan's epipolymorphism of an m-tuple #13
Mathematical definition in Landan, G., Cohen, N. M., Mukamel, Z., Bar, A., Molchadsky, A., Brosh, R., et al. (2012). Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues. Nature Genetics, 44(11), 1207–1214. doi:10.1038/ng.2442.
Include function to compute this and also a function to create the plots of epipolymorphism vs. average methylation in the same paper.
Mathematical definition in
Landan, G., Cohen, N. M., Mukamel, Z., Bar, A., Molchadsky, A., Brosh, R., et al. (2012). Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues. Nature Genetics, 44(11), 1207–1214. doi:10.1038/ng.2442.Include function to compute this and also a function to create the plots of epipolymorphism vs. average methylation in the same paper.