An R package with tools for analysing, managing and visualising co-methylation data. Loosely speaking, co-methylation is the correlation structure of DNA methylation.
zeta, defined in Landan et al. Nature Genetic 2012 (although not called 'zeta'), is the average level of methylation for all reads that overlap all methylation loci in the m-tuple. This is generally not equivalent to the average beta values of the m-tuple. Because of this, I will not include this as part of the CoMeth virtual class or any of its concrete subclasses.
zeta, defined in Landan et al. Nature Genetic 2012 (although not called 'zeta'), is the average level of methylation for all reads that overlap all methylation loci in the m-tuple. This is generally not equivalent to the average beta values of the m-tuple. Because of this, I will not include this as part of theCoMethvirtual class or any of its concrete subclasses.