RDadarwal / Diffusion-MRI

Jupyter notebooks for analyzing diffusion MRI data in order to calculate DTI, DKI, NODDI, SS3T-CSD, and MSMT-CSD modelled parametric maps
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Diffusion-MRI (dMRI)

These Jupyter notebooks include diffusion MRI data analysis to calculate Diffusion Tensor Imaging (DTI), Diffusion Kurtosis Imaging (DKI), Neurite Orientation Dispersion and Density Imaging (NODDI), Single-Shell 3-tissue Constrained Spherical Deconvolution (SS3T-CSD), and Multi-Shell Multi-Tissue Constrained Spherical Deconvolution (MSMT-CSD) modeled parametric maps.

Pre-processing Jupyter notebook includes data denoising using DIPY, susceptibility-induced distortion correction using FSL TOPUP and eddy current-induced distortion and motion correction using FSL EDDY.

Note: estimation of DKI, NODDI, and MSMT-CSD modeled parametric maps require diffusion-weighted MRI data acquired for at least three b-values (e.g. 0, 1000, 2000).

Dependencies

Dependencies to use these Jupyter notebooks are:

Citation

Messinger, A., Sirmpilatze, N., Heuer, K., Loh, K.K., Mars, R.B., Sein, J., Xu, T., Glen, D., Jung, B., Seidlitz, J., Taylor, P., Toro, R., Garza-Villarreal, E.A., Sponheim, C., Wang, X., Benn, R.A., Cagna, B., Dadarwal, R., Evrard, H.C., Garcia-Saldivar, P., Giavasis, S., Hartig, R., Lepage, C., Liu, C., Majka, P., Merchant, H., Milham, M.P., Rosa, M.G.P., Tasserie, J., Uhrig, L., Margulies, D.S., Klink, P.C., 2020. A collaborative resource platform for non-human primate neuroimaging. NeuroImage 117519. https://doi.org/10.1016/j.neuroimage.2020.117519

Example dataset:

In vivo diffusion MRI data (Macaca mulatta brain scanned at Siemens 3T) provided by the Aix-Marseille Université at the PRIMatE Data Exchange (http://fcon_1000.projects.nitrc.org/indi/indiPRIME.html).