Overview
Welcome to the Interactive Safety Graphics home page. We make open source interactive graphics for monitoring clinical trial safety. Check out a sample graphic along with its paired clinical workflow based on the medical literature, or explorer your own data using the safetyGraphics R package shown below.
Background
The Interactive Safety Graphics (ISG) subteam of the ASA Biopharm-DIA Safety Working Group is an interdisciplinary effort that, amongst other things, seeks to provide a clinical safety workflow for monitoring during clinical development in an open source model. For more details see:
- About Page - learn more about our team's motivation and see a full list of team members
- Road Map - learn more about our active and planned projects
- Contribution guidelines - learn about how to contribute code to the project
safetyGraphics R Package
The safetyGraphics R package makes it easy for users to evaluate thier own clinical trial safety data in R. The package provides a simple workflow to load lab data from clinical trials (AdAM or SDTM preferred).
To learn more you can:
- See the package on CRAN
- Download the clinical workflow
- Explore the github repo for the package, or read through the package vignettes:
- Intro to safetyGraphics - Introductory vignette providing the overview of the package.
- Chart Configuration Vignette - Details about the charting process including technical specifications and step-by-step instructions
- Cookbook Vignette - A series of examples showing how to initialize the safetyGraphics Shiny app in different scenarios
- Technical FAQ Vignette - vignette discussing security, validation and other technical issues
- Check out the underlying javascript library used to create the Hepatic Safety Explorer Chart
- Try out a hosted version of the shiny app
- Check out other interactive graphics for safety monitoring. We also wrote a paper about these. Our plan is to add some of them to SafetyGraphics package in future releases.
- Take a look at the technical framework being used to create the chart
- Explore some of our presentations
- See the poster we presented at RStudio::conf(2019)
- See the slides or video introducing safetyGraphics v2.0 from R in Pharma 2020