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StructuralGenomicsConsortium
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CNP16-iminoquinone-SarsRdRp-mechanstic-study
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Exploring Reactivity of RA-0001351 with Various Nucleophiles
#10
qxsml
opened
1 month ago
0
Synthesis and Characterization of the Adduct Formed Between RA-0001351 and Protected Cysteine
#9
qxsml
opened
1 month ago
0
Computational Modeling Needed to Test Covalent Protein Modification Mechanism
#8
mattodd
opened
1 month ago
11
Attempted reactions of RA-0001351 with protected cysteine under buffer conditions aiming to confirm that the made cysteine-RA1351 adduct was formed under buffer conditions.
#7
qxsml
opened
4 months ago
4
google sheet update
#6
rahmanszsaleem
closed
4 months ago
0
Attempted synthesis of iminoquinone-cysteine adducts: a protected cysteine-RA-1351 adduct was made, characterized using LCMS and 1H NMR, but C13 missing signals
#5
qxsml
opened
8 months ago
6
Attempted monitoring/following the reaction of N-acetyl cysteine with RA-0001351 using NMR.
#4
qxsml
closed
6 months ago
2
Conditions for the cysteine assay
#3
qxsml
closed
4 months ago
1
Synthesis of the Original Hit "RA-0001351" and the subsequent cysteine adduct.
#2
qxsml
opened
9 months ago
10
using N-acetyl cysteine as the substrate
#1
qxsml
closed
2 months ago
7