StructuralGenomicsConsortium / CNP24-NSP10_14-Frags

This project aims to develop potent inhibitors of NSP14/NSP10 for the treatment of (CoV-19), Targeting the NSP14 and NSP10 interacting interface with small molecules or peptides could be a smart strategy to obstruct replication processes of coronaviruses (CoVs).
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18 fragments - overlapping #2

Closed Sharifahsabrina closed 4 months ago

Sharifahsabrina commented 6 months ago

An overlap between fragments 18, 15, 12, 11, 10, 8, and 3 can be observed at the NSP14 and NSP10 interface based on fragalysis. The cluster of these fragments bound to the NSP14 protein is seen in the images below.

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mattodd commented 4 months ago

Closing because this information is now in the wiki.