StructuralGenomicsConsortium / CNP24-NSP10_14-Frags

This project aims to develop potent inhibitors of NSP14/NSP10 for the treatment of (CoV-19), Targeting the NSP14 and NSP10 interacting interface with small molecules or peptides could be a smart strategy to obstruct replication processes of coronaviruses (CoVs).
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Earlier analysis of the interface fragments #7

Closed mattodd closed 7 months ago

mattodd commented 7 months ago

Carried out by @shanursabrina at an early stage of the project. Pasting here so as to archive, since no longer needed on the wiki.

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mattodd commented 7 months ago

Closing as superseded by newer material on the wiki, and fragments can be viewed directly on Fragalysis at https://fragalysis.diamond.ac.uk/viewer/react/preview/target/NSP14/tas/lb18145-1 (there are also a couple of minor structural errors in the above e.g. methylene missing from 1).