We would like to compare the RPF densities in two conditions. Can XPRESSpipe display the plots on the same Y-axis scale?
> This functionality is not built in, but I can add this functionality. This is a good idea, I can just add an additional
flag to set a y-axis maximum.
We are interested in comparing the coverage across conditions. Simply selecting a “representative” trace could be misleading.
We would prefer to consider the average coverage/position for the samples in each condition. Do you think this can be done?
Would we need to normalize the coverage in each sample for the total counts in that RPF library?
> We could add this as a feature, or we could average the txt files between replicates. It would likely be preferable to
average coverage to total RPF counts. This is not currently available, but could be integrated into the software with minimal
effort (I hope).
Summary from an email request: