aertslab / AUCell

AUCell: score single cells with gene regulatory networks
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GO and pathway enrichment analysis #13

Closed nfancy closed 1 year ago

nfancy commented 3 years ago

Hi,

Thanks for the package. This is more of a query than an issue. I was wondering if it would be appropriate for GO and pathway enrichment analysis similar to GSEA. If yes, what method do you recommend for p-value calculation and multiple testing correction? What is your recommendation in terms of effect size calculation of the enrichment score base on a trait (for example Disease vs Control)?

Looking forward to hearing from you soon.

Nurun

s-aibar commented 1 year ago

Sorry, for questions on how to use the package, see: https://github.com/aertslab/AUCell/issues/26