PNAS_2015-25510 Supplemental Files Overview

Antibody_sequence_analysis.zip Reports the pipeline and custom scripts for bioinformatic sequence analysis.

Naive_antibody_germline_reversion.zip Reports the workflow used to prepare naive antibody sequences for computational modeling.

Statistical_analysis.zip Code for statistical analyses of sequence and structural data.

antigen_exp_Donor1_pt1.tar.gz and antigen_exp_Donor1_pt2.tar.gz Contain the top-ranking structural models for each antibody modeled in the Donor 1 Antigen-Experienced B cell repertoire. Models are in PDB format.

antigen_exp_Donor2_pt1.tar.gz and antigen_exp_Donor2_pt2.tar.gz Contain the top-ranking structural models for each antibody modeled in the Donor 2 Antigen-Experienced B cell repertoire. Models are in PDB format.

naive_Donor1_pt1.tar.gz and naive_Donor1_pt2.tar.gz Contain the top-ranking structural models for each antibody modeled in the Donor 1 naive B cell repertoire. Models are in PDB format.

naive_Donor2_pt1.tar.gz and naive_Donor2_pt2.tar.gz Contain the top-ranking structural models for each antibody modeled in the Donor 2 naive B cell repertoire. Models are in PDB format.