The third phase, Hack, of the BOSS Events consists of the miniprojects. Our participants get to learn about reproducibility by reproducing research that has been done before or contributing to ongoing work. The projects will allow our participants to practice the skills they have learnt througout the workshops.
Aim:
The study will aim at trying to describe the current status of Open Science in Africa. This will involve coming up with a review through literature search from the current published manuscript on Open Science in Africa. Open Science in Kenya: Where are we? Manuscript will serve as a starting point. The aim is to expand the study started in 2018.
Manuscript:
Mwangi, K. W., Mainye, N., Ouso, D. O., Esoh, K., Muraya, A. W., Mwangi, C. K., Naitore, C., Karega, P., Kibet-Rono, G., Musundi, S., Mutisya, J., Mwangi, E., Mgawe, C., Miruka, S., Kibet, C. K., & OpenScienceKE Collaborators (2021). Open Science in Kenya: Where Are We?. Frontiers in research metrics and analytics, 6, 669675. https://doi.org/10.3389/frma.2021.669675
Objective:
Comment on this issue to take part in this project.
Aim:
Create a handbook to facilitate proper research data management in Resource constrained settings. In this project, the participants will be expected to evaluate and compare the various genomics data management approaches that are available and to test how easy it is to set-up and use the tools. The focus is on genomics.
Guide: Use the TuringWay Handbook as a guide on how to create the book. In the Turing-way: Welcome — The Turing Way
Objective: Answer the following questions:
Comment on this issue to take part in this project
Aim:
The study will aim at reproducing a meta-genomics study performed in Kenya. The study and data will be selected and obtained from the GOLD or any database. Participants will be required to understand the study, reproduce it using the same or alternative bioinformatics tools used in the study and report on information obtained from analysis.
Manuscript:
Langat, S. K., Eyase, F., Bulimo, W., Lutomiah, J., Oyola, S. O., Imbuga, M., & Sang, R. (2021). Profiling of RNA Viruses in Biting Midges (Ceratopogonidae) and Related Diptera from Kenya Using Metagenomics and Metabarcoding Analysis. mSphere, 6(5), e0055121. https://doi.org/10.1128/mSphere.00551-21
Objective:
Comment on this issue to take part in this project
Aim:
The study uses several genomic and bioinformatics approaches. In this project, participants will be required to reproduce the genomic analysis carried out in the study. The data will be available from NCBI. You are expected to: Download the sequence data programmatically, carry out DNA sequence pre-processing and de novo assembly and perform genome annotation of the plant of interest.
Manuscript:
Chang, Y., Liu, H., Liu, M., Liao, X., Sahu, S. K., Fu, Y., Song, B., Cheng, S., Kariba, R., Muthemba, S., Hendre, P. S., Mayes, S., Ho, W. K., Yssel, A. E. J., Kendabie, P., Wang, S., Li, L., Muchugi, A., Jamnadass, R., … Liu, X. (2018). The draft genomes of five agriculturally important African orphan crops. 8, 1–16. https://doi.org/10.1093/gigascience/giy152
Objectives: Come with a detailed report answering the following:
Comment on the issue to take part in this project.
Aim:
The study will use bioinformatics approaches. In this project, participants will be required to use the provided files described in the manuscript to perform data preprocessing, variant calling, alignment, assembly and phylogenetic analysis as described by the manuscript. Participants will use any pipeline used in the study, interpret the output files, critique it, compare with other available pipelines or even come up with a better pipeline.
Manuscript:
Casimiro-Soriguer, C. S., Perez-Florido, J., Fernandez-Rueda, J. L., Pedrosa-Corral, I., Guillot-Sulay, V., Lorusso, N., Martinez-Gonzalez, L. J., Navarro-Marí, J. M., Dopazo, J., & Sanbonmatsu-Gámez, S. (2021). Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain). Viruses, 13(5), 836. https://doi.org/10.3390/v13050836
Objective:
Comment on the issue to take part in this project
The project leads of each project are partners of BHKi and OpenScienceKe.
Our workshop participants will proceed to this phase and will be divided into groups to take part in different projects.
All the projects will adopt an open approach and will be published or updated in GitHub. The participants will also present their works in the BOSS conference happening in March 2022.
Follow the individual project GitHub repos to contribute.
All rules and regulations stipulated in CoC of both BHKi and Open Science Kenya still apply. However, below are some specific rules and regulations that will apply as you work in teams in your mini project/hackathon: