local_scfc

Calculate structure-function coupling at a local level as in Esfahlani et al (2021).

dependencies and requirements

This script uses MATLAB. It was tested using MATLAB 2020a on macOS Mojave 10.14.6. It requires no additional software packages.

installation and usage

Download and unzip the directory, open MATLAB, and then navigate to wherever you downloaded the files. You can run the script from within that directory.

what is here

• Group-representative sc/fc/euclidean distance in 400-node parcellation.
• Directory containing functions for generating predictors based on sc matrix.
• Example script to implement the procedure.

what does the script do?

1. Reads in sc/fc/euclidean distance data
2. Generates a set of predictors
3. Calculates local (regional) correlations of predictors with FC.

if you want to apply this method to your data

• Replace variables sc, fc, d with your own structural connectivity, functional connectivity, and inter-regional Euclidean distance matrix.

Runtime for entire script is < 10 s.

If you use this code, please cite: Esfahlani, F. Z., Faskowitz, J., Slack, J., Misic, B., & Betzel, R. (2021). Local structure-function relationships in human brain networks across the human lifespan. bioRxiv. (link to paper)