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broadinstitute / cmQTL

High-dimensional phenotyping to define the genetic basis of cellular morphology
BSD 3-Clause "New" or "Revised" License
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General questions on Manuscript #61

Closed jatinarora-upmc closed 2 years ago

jatinarora-upmc commented 3 years ago

Are cells in colonies more similar to each other and to intermediate cells than to isolate cells?

This is at donor level.

The plots shows comparison of variance of individual features between isolate and colony cells (zooming-in from first to last). Each dot is one feature. image image image image

Comparison between intermediate and colony cells. Each dot is one feature. image image image image

How much heritable are morphology traits?

PCA of cells / well / donors based on morphology traits.

This is at donor level and all cells, and using all features

image

jatinarora-upmc commented 3 years ago

@shntnu @mtegtmey @bethac07 and Emily, Dear guys, i have shared with the google doc link to manuscript. I think ms requires your input in methods section. Could you please help? The link to the ms is https://docs.google.com/document/d/1hDAJDfndiFTs6I8Xxm9pT4JvsqbmVeQF/edit