The most critical downside to AI is that its inefficiency is directly related to its data quality. Presently there are very few methods available that are used to protect the data from being attacked in the real time applications. But there is no commonplace in terms of defence technology that is being used for various types of attacks, in these situations the need for a generic method is highly needed for defending against those poisoning attacks, so we have come up with the defence technique that is called as De-Pois Defence method