Cell type Aware analysis for RNA-seq data
This is the R package for cell type aware analysis of RNA-seq data. The input are bulk RNA-seq data and cell type fraction estimates for a set of samples, and relevant variables of these samples, include a variable of interest for differential expression analysis as well as covariates.
To install this package in R, use
library("devtools");
install_github("Sun-lab/CARseq")Jin, C., Chen, M., Lin, DY. et al. Cell-type-aware analysis of RNA-seq data. Nat Comput Sci 1, 253–261 (2021). https://doi.org/10.1038/s43588-021-00055-6
A preprint of the paper can be downloaded from: https://github.com/Sun-lab/CARseq/blob/master/inst/docs/Jin_et_al.-2021-Cell-type-aware_analysis_of_RNA-seq_data.pdf