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coriell-research / ursaPGx

R Package for Star Allele Annotation
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Input data type #3

Open EmMaKaa opened 2 weeks ago

EmMaKaa commented 2 weeks ago

Hi,

in your paper, you used 30x WGS data for the analyses. I'm interested in whether this tool would be suitable for imputed GWAS data?

Thank you!

jcalendo commented 2 weeks ago

We recommend against using imputed data as input for ursaPGx. ursaPGx assumes that all variants (rare and common) are being directly measured. All errors in imputation will directly result in errors in the ursaPGx output annotations.