cytomining / pycytominer

Python package for processing image-based profiling data
https://pycytominer.readthedocs.io
BSD 3-Clause "New" or "Revised" License
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Question about noise removal #242

Open bethac07 opened 1 year ago

bethac07 commented 1 year ago

Purely a question - was it ever considered to use CV rather than pure standard deviation in this feature? This is an obviously artificial example, but to me I would feel 'b' is more noisy in that across my feature the fold change is really large, but since 'a' has a higher absolute value it gets removed first

image
gwaybio commented 1 year ago

was it ever considered to use CV rather than pure standard deviation in this feature?

I don't believe so. @ruifanp developed the approach, so he might have some more insight.

In general, I think that we're definitely open to adding functionality here!