digitalcytometry / ecotyper

EcoTyper is a machine learning framework for large-scale identification of cell states and cellular ecosystems from gene expression data.
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The differences of Tutorial 2 with Tutorial 5 #23

Closed QianhuiXu closed 1 year ago

QianhuiXu commented 2 years ago

Dear EcoTyper team,

We want to use ecotyper in our scRNA-Seq dataset. But I was confused with the differences of Tutorial 2 with Tutorial 5. Which analysis pipeline should I follow to analyze cell type-specific transcriptional states and co-association patterns in our scRNA-Seq dataset? I'm really at a loss as to how to proceed, and any guidance would be much appreciated!

Sincerely, Qianhui Xu

BALuca commented 2 years ago

Hi,

Tutorial 2 allows you to label your single cells to the cell states that we already defined in carcinoma or lymphoma. Tutorial 5 allows you to discover de-novo cell states and ecotypes from your scRNA-seq data. So, my sense is that you want to try Tutorial 5.

Bogdan