draeger-lab / C_striatum_wetlab

This repository contains data generated in the wet lab need for characterization and validation of strain specific GEMs
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publication todos wetlab #4

Closed famosab closed 10 months ago

famosab commented 1 year ago

We want to publish all the models in combination with refineGEMs and the corresponding drylab results. This issue serves as ToDo-list and overview on what has been done.

famosab commented 1 year ago
famosab commented 1 year ago
famosab commented 1 year ago

The identification of C. striatum from clinical specimens requires a high index of suspicion since colonies resemble coagulase-negative staphylococci and may be discarded as commensals. Further, species identification of diphtheroids is important since some of these are now recognized as potential pathogens. Identification of C. striatum has presented a problem, particularly for resource-poor settings because conventional phenotypic tests are time-consuming and insufficiently discriminative. (shariffCorynebacteriumStriatumEmerging2018)

This might be interesting to put into the Introduction to show how important metabolic knowledge is. We would need another publication that showcases how metabolic models are used for identification purposes though.