Project 3: Long Read Virus Assembly

[Kiage24]

This project is my first choice.

Reasons:

1. Previous internships at a viral center in a research institute influenced my budding interests in virology besides human health.
2. Genome assembly throughout the course has been addressed from a theoretical point of view unlike other areas. The project would develop my skills in genome assembly pipelines.
3. I have had no prior exposure to long read analysis and would like to gain exposure.

[Kauthar-Omar]

FIRST CHOICE

1. To gain skills in analyzing long reads.
2. To explore the viral research niche.
3. To gain skills in developing whole genome assembly pipelines.

[tefer0]

THIRD CHOICE

• This mini project will enable me make use of the knowledge and skills gained on long read assembly from the Residential training and other prior relevant training and class knowledge.
• This mini project will also improve my analysis skills in long reads viral genomes data analysis.

[fredrickkebaso]

Third choice.

Reasons

Long read assembly has been theoretical so far, this project presents a noble opportunity to practically apply the various tools I have been exposed to and learn the intricacies that accompany their application.

[ndugwahenry]

My-second choice

• This project will equip me with the skills required to analyze long reads as they are becoming more popular these days.
• Also learn more about viral genome

[sephoh]

Third choice: Reason: 1) have worked with ONT long reads metagenomic for pathogen profiling. This project allow expose me to single cell assembly(virus assembly). 2) Im interested in comparing how long reads assembly for viral assembly compare with primer walking technique. 3)Long reads are better for repetitive DNA sequence common in eukaryotic cells. Viruses have non- repetitive sequence to reduce the effective size of the cell. I like the project challenge to see how this seemingly contradicting fact resolves.

[manasealoo]

Third Choice

• Gain skills in long read analysis,key tools,and viral genome assembly

[totodingi]

First Choice

Genome assembly is not only resource-intensive but also time-consuming. Having worked on a project that required an assembly phase before, I have had the opportunity of benchmarking the performance of several assemblers. For this project, it would be interesting to seek various hacks on how to reduce the resource consumption and time taken for assembly, while at the same time maintaining the quality of the assembled reads. It also will be a plus for me to learn how to efficiently handle long reads.