NOMePlot - A Webtool for the analysis of NOMe and Bisulfite data
NOMePlot is a webtool that facilitates the analysis of Nucleosome Occupancy and Methylome (NOMe) and Bisulfite (BS) sequencing data generated using Sanger or High-throughput sequencing (NOMe-PCR, NOMe-seq, BS-PCR and BS-seq).
This web application is easy to use and does not required bioinformatic skills. Input sequences for sanger sequencing analysis must be provided in fasta format while input data for high-throughput sequencing must be provided as a bam file. The user-interface is self-explanatory.
NOMePlot has been developed with R/Bioconductor packages and Shiny. Source code for local installation is available from GitHub.
NOMePlot operates under the GNU General Public License version 3.
Citing NOMePlot
Requena F, Asenjo HG, Barturen G, Martorell-Marugán J, Carmona-Sáez P and David Landeira. NOMePlot: analysis of DNA methylation and nucleosome occupancy at the single molecule. Scientific Reports. May 31;9(1):8140. doi: 10.1038/s41598-019-44597-2. 2019. Abstract.