CellTypeAnalyses_Darmanis

This repository contains the full code for the cell type analyses applied to the Darmanis et al. single-cell RNAseq data in the manuscript "INFERENCE OF CELL-TYPE COMPOSITION FROM HUMAN BRAIN TRANSCRIPTOMIC DATASETS ILLUMINATES THE EFFECTS OF AGE, MANNER OF DEATH, DISSECTION, AND PSYCHIATRIC DIAGNOSIS" (http://biorxiv.org/content/early/2016/11/25/089391)

by *Megan Hastings Hagenauer, Ph.D.1, Jun Z. Li, Ph.D.2, David M. Walsh, Psy.D.3, Marquis P. Vawter, Ph.D.3 Robert C. Thompson, Ph.D.1, Cortney A. Turner, Ph.D.1, William E. Bunney, M.D.3, Richard M. Myers, Ph.D.4, Jack D. Barchas, M.D.5, Alan F. Schatzberg, M.D.6, Stanley J. Watson, M.D., Ph.D.1, Huda Akil, Ph.D.1

1Mol. Behavioral Neurosci. Inst., Univ. of Michigan, Ann Arbor, MI, USA;  2Genet., Univ. of Michigan, Ann Arbor, MI, USA;  3Univ. of California, Irvine, CA; 4HudsonAlpha Inst. for Biotech., Huntsville, AL, USA; 5Stanford, Palo Alto, CA, 6Cornell, New York, NY, USA 

Please note that this code is not easily generalizable - it primarily represents the documentation for all analyses used in our paper. For those of you who are interested in applying similar techniques to your own data, we do have a simplified, generalized version available at https://github.com/hagenaue/BrainInABlender.