SynergyFinder: Calculate and Visualize Synergy Scores for Drug Combinations

Introduction

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.

Support

If you have any problems in using SynergyFinder, please contace Liye He (liye.he@helsinki.fi)

Copyright & License

Code released under the Mozilla Public License 2.0.

Citation

In case you use the package in your work, we do appreciate a cition to our publication:

He L, Kulesskiy E, Saarela J, Turunen L, Wennerberg K, Aittokallio T, et al. (2018) Methods for High-throughput Drug Combination Screening and Synergy Scoring. In: von Stechow L, editor. Cancer Systems Biology: Methods and Protocols. New York, NY: Springer New York. P351-98.