hms-dbmi / OncoThreads

OncoThreads longitudinal cancer genomics visualization project.
http://oncothreads.gehlenborglab.org
MIT License
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Patient Grouping #248

Closed wangqianwen0418 closed 3 years ago

wangqianwen0418 commented 3 years ago

several options of user encoding:

❓ more experiments & discussions are needed

wangqianwen0418 commented 3 years ago

clustering method

:link: https://github.com/hms-dbmi/OncoThreads/blob/version2/src/modules/TemporalHeatmap/UtilityClasses/clusterfck.js

Patient grouping is based on a hcluster algorithm. It is a bottom-up method. Every time, the algorithm merge two clusters with the smallest distance.

the original version is modified as below:

wangqianwen0418 commented 3 years ago

Observe State Transitions❓

I found it is not always easy to observe transition in Sankey diagram. For example, in the figure below, it is possible that there are only sequence [A, C, E] and [B, C, D], no [B, C, E] exists. image

Does it matter?

If it doesn't matter, does it mean that we only need to care the state transition between two timepoints?