After installing the tool, make sure to rebuild the main docking bar so that the menu entries for control of the Interactive Profiler appear.
The three different modes of the Interactive Profiler are accessible from the "Extras" menu in the main docking bar as well as via keyboard shortcuts (see the tool tips of the menu entries inside "Extras" for help).
Click "Extras", "Profile Block" to enter a block and profile that block.
Click "Extras", "Profile Last Block Again". If you profiled a block and were not happy with the results, you can profile the block again after having made changes to the underlying code to quickly see how the changes affected performance. Notice the entries for "Last Execution" and "Delta" in the duration tree on the right of the results pane.
Click "Extras", "Profile Last Block Again". This simply spies on everything that's happening until you press "Stop".