Changeo-O is part of the Immcantation analysis framework for Adaptive Immune Receptor Repertoire sequencing (AIRR-seq). Change-O provides tools for processing the output of V(D)J alignment tools, assigning clonal clusters, and reconstructing germline sequences.
It's not documented why some records fail MakeDb. Currently, our criteria seem to be lack of V, J or junction sequence; ie, those records that IMGT failed to align. I think the criteria are fine, we just need to document it somewhere.
While we're at it, I think the list of required fields isn't accurate. JUNCTION_LENGTH and D_CALL are no longer needed, yes?
Original report by Jason Vander Heiden (Bitbucket: javh, GitHub: javh).
It's not documented why some records fail MakeDb. Currently, our criteria seem to be lack of V, J or junction sequence; ie, those records that IMGT failed to align. I think the criteria are fine, we just need to document it somewhere.
While we're at it, I think the list of required fields isn't accurate.
JUNCTION_LENGTH
andD_CALL
are no longer needed, yes?