.. image:: https://img.shields.io/pypi/dm/changeo :target: https://pypi.org/project/changeo .. image:: https://img.shields.io/static/v1?label=AIRR-C%20sw-tools%20v1&message=compliant&color=008AFF&labelColor=000000&style=plastic :target: https://docs.airr-community.org/en/stable/swtools/airr_swtools_standard.html
Change-O is a collection of tools for processing the output of V(D)J alignment tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and reconstructing germline sequences.
Dramatic improvements in high-throughput sequencing technologies now enable large-scale characterization of Ig repertoires, defined as the collection of trans-membrane antigen-receptor proteins located on the surface of B cells and T cells. Change-O is a suite of utilities to facilitate advanced analysis of Ig and TCR sequences following germline segment assignment. Change-O handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of clustering methods for assigning clonal groups to Ig sequences. Record sorting, grouping, and various database manipulation operations are also included.
IMPORTANT! Change-O has moved to https://github.com/immcantation/changeo
To update Git configuration settings:
git config user.email "your-gh-user@email.com"
git config user.name "your-gh-user-name"
git remote set-url origin git@github.com:immcantation/changeo.git