iqbal-lab-org / minos

Variant call adjudication
MIT License
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Depth tags and filter fixes #111

Closed martinghunt closed 3 years ago

martinghunt commented 3 years ago

Renames VCF tag DP to COV_TOTAL (which is the total reads mapped to the site by gramtools). New tags: ALLELE_DP = mean read depth of ref and each alt; DP = ALLELE_DP of the allele called by the genotyper.

New filter added on DP, where if the read depth is more than (default) 3 standard deviations from the mean depth, then it fails the filter.