Right now the escape plots show the \beta values estimated by the model. Particularly with non-one Hill coefficients, but also more generally, the relationship between \beta and escape can differ across replicates and/or antibodies.
I propose to also make plots showing how each mutation is predicted to impact the ICXX (eg, IC90) where that is what would be shown in the heatmap rather than the \beta values. In some cases, this could be more interpretable or illustrative than plotting the \beta values.
@Bernadetadad @fwelsh @caelanradford, I just wanted to solicit any feedback you had about this idea from looking at your data before starting this.
Right now the escape plots show the
\betavalues estimated by the model. Particularly with non-one Hill coefficients, but also more generally, the relationship between\betaand escape can differ across replicates and/or antibodies.I propose to also make plots showing how each mutation is predicted to impact the ICXX (eg, IC90) where that is what would be shown in the heatmap rather than the
\betavalues. In some cases, this could be more interpretable or illustrative than plotting the\betavalues.@Bernadetadad @fwelsh @caelanradford, I just wanted to solicit any feedback you had about this idea from looking at your data before starting this.