LX9R3-BASED USB MEGADRIVE DEVKIT
You'll need an lx9/r3 board:
https://github.com/makestuff/lx9/tree/r3
...and a umdkv2-lx9/r1 board:
https://github.com/makestuff/umdkv2-lx9/tree/r1
You can then follow the instructions in the Wiki:
https://github.com/makestuff/umdkv2/wiki