Open adamcatto opened 4 months ago
Hi @adamcatto,
Thank you for your suggestion, I don't see why this makes an improvement in the current pipeline and/or its benifits over all. We don't currently have the option of removing internal repeated nucleotides. (Please expect delays due to travel and will be back on May 04 EST).
Thank you, Arun.
I think for some reads there may be strings of identical nucleotides that are technical artifacts which should be removed. In any case, I have forked the repository and added an option to remove repeated nucleotides ≥ a given length. You can view the changes here if it sounds interesting: https://github.com/adamcatto/miRge3.0/commit/8709dfe44c22d743e358484ad2e889966b8786cf
Is there an option in miRge to trim off nucleotides that are repeated more than
k
times? e.g.ACGT[A* >= k]TGCA
gets trimmed toACGTTGCA
. I know this can be done prior to running the miRge pipeline but it would be nice to just include as an argument in the miRge run script.