mpxv-lineages / lineage-designation

Official place for proposals and details around monkeypox virus lineage designations
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Proposal for a sublineage of A.2 [4 sequences, 1x US, 1x UK, 2x India] #15

Closed corneliusroemer closed 2 years ago

corneliusroemer commented 2 years ago

Outside of the 2022 outbreak lineage B.1, this year has seen around a dozen of submissions from clade A.2 - roughly a percent of this year's sequences.

There's a cluster of 4 sequences in A.2 that may be worth designating due to the likely under sampled nature of the A.2 lineage.

There are 4 sequences in this cluster (the two Indian sequences have been resequenced from culture, I'm not counting them here)

image

2 of these sequences, the Florida and UK ones are on Genbank, the Indian sequences are on GISAID.

Lineage defining mutations are:

C25072T
G36898A
G42183A
C42903T
G50346A
C54268T
G79406A
G105746A
A140492C
C142498T
C157737T
C161152T
C179537T