fishHook
R package for applying Gamma-Poisson regression to identify statistical enrichment or depletion of somatic mutations in arbitrary (sets of) genomic intervals after correcting for genomic covariates, e.g. replication timing, sequence context, chromatin state.
Installation
-
Install devtools from CRAN (if you don't have it already)
install.packages('devtools') -
Install gUtils
devtools::install_github('mskilab/gUtils') -
Install fishHook
devtools::install_github('mskilab/fishHook')
Documentation
Attributions
Marcin Imielinski - Assistant Professor, Weill-Cornell Medical College. Core Member, New York Genome Center.
Zoran Gajic - Undergraduate Research Assistant, Rutgers University, Weill Cornell Medicine, New York Genome Center.