Closed mattodd closed 3 years ago
Fine with me
Perfect!
Fine by me, I'll be using the extra time to weigh out our compounds going to DNDi! Was hoping to get them out by end of this week but looks like it will be early next week instead - I'll post an update when they've shipped.
I hereby propose we call these going forward Pseudomeetings
Thoughts everyone?
@mattodd I think we did get some preliminary data re tox: https://github.com/opensourceantibiotics/Series-2-Diarylimidazoles/blob/master/Cytotox/Tox2.jpg
@mattodd @danaklug Assuming the data is correct above - perhaps this might be worth exploring?
@MFernflower we have the oxetane analog up for purification so maybe hold off and wait for that one?
@lferrins Do open a github issue for that particular compound once it's purified - I bet it will be quite the interesting gem to add to our SAR tables
@MFernflower once it is ready to ship I will open a new issue!
Hi all - meeting today? As far as I can tell:
0) We're awaiting crucial tox data from Alex.
1) we are still working on the action items from last time (#68) <-- it's on me to upload recordings, will do.
2) @danaklug posted a really nice summary of chemical next steps here that includes the molecules @flavioemery volunteered to make and some targets for @Giada-chem, and @MFernflower reminded us that we need to purchase a couple of amides.
3) @edwintse is looking into purifying the Hypha metabolite, and when we have it it can be added to @loriferrins ' compounds for evaluation by Paul Stapleton (who is happy to do this, just spoke with him).
4) Dana is shipping stuff to DNDi, I'm writing a newsletter (though I have to write something for World Malaria Day first..!)
So I suggest we skip this week, gain 30 minutes of individual quality science time (always a pleasure, right @drc007?) and reconnect next week. Any howls of disappointment?