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Updated project score dataset: Missing diseaseCellLines object and adding publication #3222

Open prashantuniyal02 opened 4 months ago

prashantuniyal02 commented 4 months ago

Background

  1. The updated project score dataset now has pan-cancer annotation for genes that were found across different type cancer cell lines. These genes are now assigned with the EFO (MONDO_0004992) "cancer". However these associations don't have disease cell lines attached. How that would impact on the project score widget?
Example associations endpoint response: ``` { "targetFromSource": "SOX10", "diseaseFromSource": "pancancer", "diseaseFromSourceMappedId": "MONDO_0004992", "resourceScore": 78.98182, "targetFromSourceId": "ENSG00000100146", "literature": [ "38215750" ], "datasourceId": "crispr", "datatypeId": "affected_pathway" } ```

There's no diseaseCellLines object that is used for generating the drawer

Current implementation:

image
  1. Adding a literature column, given publication is available. For this source the link to the publication don't need to be put in every row of the evidence given it is constant, however the header of the widget could/should contain the link to the publication.

Tasks

See details here.

buniello commented 4 months ago

Discussed with @DSuveges and decided: the pan-cancer associations are dropped from the updated evidence set

buniello commented 4 months ago

For the second task (literature field) one option would be to add a Pacini et al, 2024 link to the Project Score widget header, after the Project Score link. (just a suggestion if this is easier for FE)

Screenshot 2024-02-15 at 15 31 26

ireneisdoomed commented 4 months ago

Wouldn't it be useful for the work of timestamping evidence (https://github.com/opentargets/issues/issues/2739) to include the PMID in each evidence? The FE could display in the widget header.

buniello commented 4 months ago

Discussed in team leads meet: no action taken on the Adding a literature column task for now. Link to data source contains new reference.