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Issue tracker for Open Targets Platform and Open Targets Genetics Portal
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Genetics Variant page review #3601

Open prashantuniyal02 opened 2 days ago

prashantuniyal02 commented 2 days ago

General

Variant page

Header:

Widget order? In silico (V) > VEP (V2G) > ClinVar (V2D) > Uniprot (V2D) > GWAS (V2L2D) > molQTL (V2G) > Pharmacogenetics (V2D2Dr)

Metadata:

Overall about widgets:

In silico predictors:

Variant effect predictor:

ClinVar: good

Uniprot variants: good

GWAS Credible sets and molQTL credible sets:

PheWAS plot:

buniello commented 5 hours ago

Adding these points from #3597

VEP

Column headers need clearer definitions for better understanding

When downloading VEP data, users request: 1. Uniprot links 2. Chromosome and position for genes

In-silico predictors

Suggestion: adding hyperlinks or hover text to explain prediction methods. For example, SIFT=0 means "deleterious," which is opposite to PolyPhen where a score closer to 1 indicates deleterious