primaryodors / primarydock

PrimaryOdors.org molecular docker.
Other
6 stars 4 forks source link

Memory leak fix, more active state models, and a few UI improvements. #457

Closed primaryodors closed 2 months ago

primaryodors commented 2 months ago

PrimaryDock will no longer eat up gigs of virtual memory and slow the computer to a screeching halt during soft docking.

Added a splash screen, increased the progress bar, and changed the elapsed time to be expressed in minutes and seconds.

All ORs and TAARs now have active-state models, and OR2M3's TMR5 has been adjusted to fit its agonist. The fivewinder.pepd script can be run with a factor of -11 to adjust the other OR2M/T/V receptors.

The OR2M3 test is not reliable so it has been turned off. Have to find a better algorithm to dock this ligand. Should have been done in whichever branch introduced the 2M3 test. It is out of scope for this PR.

All other tests are passing.