The Orthology Ontology

The need of a common ontology for describing orthology information in biological research communities has led to the creation of the Orthology Ontology (ORTH) on the basis of the best practices in ontology engineering. This ontology was developed in the Web Ontology Language (OWL) using Protégé. The OWL file is publicly available at http://purl.org/net/orth.

• The ORTH ontology version 2 specification is available at http://qfo.github.io/OrthologyOntology/

Issues and Activities

• The ORTH ontology 3rd version (release candidate 3a) that corrects identified issues in the ORTH ontology version 2 and includes the concept of Pangenomes.
• Orthology ontology change log to create the 3rd version (release candidate 3a) and the 2nd version release candidate (http://purl.org/net/orth_rc)
• Go to wiki for previous activities

Contributors

(In alphabetical order)

• Christophe Dessimoz, University of Lausanne and SIB Swiss Institute of Bioinformatics, Switzerland
• Dmitry Kuznetsov, SIB Swiss Institute of Bioinformatics, Switzerland
• Erick Antezana, Belgium
• Florent Villiers, France
• Hirokazu Chiba, Database Center for Life Science (DBCLS), ROIS, Japan
• Ikuo Uchiyama, National Institute for Basic Biology, Japan
• Jesualdo Tomás Fernández-Breis, Departamento de Informatica y Sistemas, Universidad de Murcia, Spain.
• María del Carmen Legaz-García, Spain
• Tarcisio Mendes de Farias, University of Lausanne and SIB Swiss Institute of Bioinformatics, Switzerland

See also

• ORTH ontology specification
• BioPortal
• AberOWL

Publication

• de Farias, T. M., Chiba, H., & Fernández-Breis, J. T. (2017, December). Leveraging logical rules for efficacious representation of large orthology datasets. In Proceedings of the 10th International Semantic Web Applications and Tools for Healthcare and Life Sciences (SWAT4HCLS) Conference. link
• Jesualdo Tomás Fernández-Breis†, Hirokazu Chiba†, María del Carmen Legaz-García, Ikuo Uchiyama (†Equal contributors). The Orthology Ontology: development and applications. Journal of Biomedical Semantics 7:34 (2016). link