feature request: adding new annotator to already annotated vcf

[antonkulaga]

When I annotated the genome with N annotators and then discover that I need one more annotator I have to run a separate job with N+1 annotators. Based on my and my teammate's experience it is a head-ache. Maybe you can add an option to add compute with new annotators without reannotating with annotators that were already used before? It can save users a lot of time.

[rkimoakbioinformatics]

@antonkulaga With the current latest version of OakVar, the following is possible.

ov run input.vcf -a clinvar This will generate input.vcf.sqlite.

ov run input.vcf.sqlite -a biogrid This will add biogrid annotation to input.vcf.sqlite.

ov run input.vcf.sqlite -a cosmic -t vcf This will add cosmic annotation to input.vcf.sqlite and generate input.vcf.vcf with the clinvar, biogrid, and cosmic annotation.

Would this work in your use case?

[antonkulaga]

We need this to be in the GUI as we mostly run annnotations from it, especially Olga as she is not a software developer

[rkimoakbioinformatics]

Ok. I'll add it to the GUI.