Welcome to NRPSpredictor2 by

Marc Roettig, Marnix Medema, Kai Blin

based on work by Christian Rausch

please cite: http://dx.doi.org/10.1093/nar/gki885 please cite: http://dx.doi.org/10.1093/nar/gkr323

This package contains the NRPSPredictor2, a program to predict adenylation domain specificity from sequence.

The predictor currently runs on Windows, Linux and on the Mac OS platform.

To build the NRPSPredictor2 please issue on the shell

ant

and the respective jar will be built and placed in the build directory.

An exemplary shell script launching NRPSPredictor2 can be found in the root directory. This script file can be adjusted if you wish to place some files to different locations (jars or model files) or use absolute path names.

Example usage:

(Linux/Mac)

if you have a multi fasta file with NRPS sequences

you issue

sh runNRPSpredictor2.sh -i examples/example.fa -s 0 -r report

if you have a file with already extracted signatures

you issue

sh runNRPSpredictor2.sh -i examples/examples.sigs -s 1 -r report

(Windows)

if you have a multi fasta file with NRPS sequences

you issue

runNRPSpredictor2.bat -i examples/example.fa -s 0 -r report

if you have a file with already extracted signatures

you issue

runNRPSpredictor2.bat -i examples/examples.sigs -s 1 -r report