Closed NkRMnZr closed 11 months ago
@AngieHinrichs May I suggest for a slight upgrade on usher, as it always have one branch fully-sampled and other branches downsampled, can it highlight the fully-sampled branch so that we can see more clearly which branch belongs to which?
Currently the biggest problem on analysis EG.5.1.1 samples is that when uploading seqs, there suddenly come up 30+ sub-branches, with each having one fully-sampled branch and other branches downsampled. However, it is really hard to distinguish which branch is fully-sampled and which is downsampled. They look all the same at the first glance.
@AngieHinrichs May I suggest for a slight upgrade on usher, as it always have one branch fully-sampled and other branches downsampled, can it highlight the fully-sampled branch so that we can see more clearly which branch belongs to which?
Currently the biggest problem on analysis EG.5.1.1 samples is that when uploading seqs, there suddenly come up 30+ sub-branches, with each having one fully-sampled branch and other branches downsampled. However, it is really hard to distinguish which branch is fully-sampled and which is downsampled. They look all the same at the first glance.
i suggest to open an issue on the usher github page.
09-21 Final update, clean up singlets/doublets, adding Branch 50-51, remove Branch 29
Adding branch 50 from former doublet with 3 seqs from Anhui Adding branch 51 from former doublet with 2 seqs from Anhui and Hubei
Remove Branch 29 that has been pulled under HK.3 now
Purge multiple singlets and doublets now merged into other branches
09-21 Final update, clean up singlets/doublets, adding Branch 50-51, remove Branch 29
Adding branch 50 from former doublet with 3 seqs from Anhui Adding branch 51 from former doublet with 2 seqs from Anhui and Hubei
Remove Branch 29 that has been pulled under HK.3 now
Purge multiple singlets and doublets now merged into other branches
Thank you
@AngieHinrichs May I suggest for a slight upgrade on usher, as it always have one branch fully-sampled and other branches downsampled, can it highlight the fully-sampled branch so that we can see more clearly which branch belongs to which?
Off the top I can't think of an easy way to do this, but an approximation would be to restore the filter on uploaded sequences. If you type "up" in the Filter input, it should auto-complete to "uploaded sequences" and then you can click on that.
As I understand it, subtrees are built in two phases, each phase contributing half of the subtree size (call it "sHalf" here, so if subtree size is 5000, sHalf is 2500):
So, when you filter to just the uploaded sequences, that should show which branches have been most densely sampled. If the number of the sequences in an ancestral branch is less than sHalf then it was probably densely sampled. The leftmost node where the first phase hits the sHalf limit is less densely sampled -- much less densely sampled if it's a node with a very large number of descendants.
There is a flaw in that approach though: sometimes when we're building a tree for an uploaded sample, we randomly get other uploaded samples that were placed nearby. And I don't know how to highlight the specific sample for which the subtree was constructed. So it is possible in some cases that those other uploaded samples are on branches that are not fully sampled. Sorry there is not really a way to distinguish those aside from just trying a single sequence when in doubt.
So, when you filter to just the uploaded sequences, that should show which branches have been most densely sampled. If the number of the sequences in an ancestral branch is less than sHalf then it was probably densely sampled. The leftmost node where the first phase hits the sHalf limit is less densely sampled -- much less densely sampled if it's a node with a very large number of descendants.
There is a flaw in that approach though: sometimes when we're building a tree for an uploaded sample, we randomly get other uploaded samples that were placed nearby. And I don't know how to highlight the specific sample for which the subtree was constructed. So it is possible in some cases that those other uploaded samples are on branches that are not fully sampled. Sorry there is not really a way to distinguish those aside from just trying a single sequence when in doubt.
Thanks for the explanation! Is it possible to highlight the first sHalf seqs? (e.g adding a filter)
In practice the first sHalf is not always the most dense branch, when it is the 4th~30th largest branch on a batch of seqs, the most dense branch is usually the 1st-3rd even if they're randomly selected from the other sHalf.
@NkRMnZr there are a few branches to put under scrutiny for a potential proposal: Branch 31, Branch 17 , Branch 15, Branch 23 , Branch 35.
England/CLIMB-CM7YMX5B/2023|EPI_ISL_18227053|2023-08-27 EG.5.1.1 > C11779T > C12525T(ORF1a:T4087I) > C4021T, G22927T(S:L455F), A24340G [Query: C11779T, C12525T, G22927T, 09/06] this one now 4 also from NZL tracking it privately
Edited 2 not 4.
@NkRMnZr branch 31 has 22 sequences on Usher : https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice6_genome_test_21e4b_148150.json?label=id:node_6975795 I think you could propose it @NkRMnZr
Please propose branch 44 low numbers but a lot of spike diversity. it has to be tracked publicly
Branch 33 is at 22 now
I'll look into those when GISAID fix that millibogo thing
I don't think this one is in here yet.
GISAID query: C6016T, T23953A, G25019C
EG.5.1.1 > G22927T(S:L455F) > C6016T, T23953A (S:F797L), G25019C (S:D1153H) First: 2023-08-28 EPI_ISL_18268474 hCoV-19/Shanghai/SCDC-XG09-13182/2023
Three more from China since then (1 on 2023-09-04 & 2 on 2023-09-11) EPI_ISL_18313145 EPI_ISL_18313147 EPI_ISL_18313152
Plus not on GISAID there are 3 from England, with an additional S:Q474K Fastas for those available here
I don't think this one is in here yet.
GISAID query: C6016T, T23953A, G25019C
EG.5.1.1 > G22927T(S:L455F) > C6016T, T23953A (S:F797L), G25019C (S:D1153H) First: 2023-08-28 EPI_ISL_18268474 hCoV-19/Shanghai/SCDC-XG09-13182/2023
Three more from China since then (1 on 2023-09-04 & 2 on 2023-09-11) EPI_ISL_18313145 EPI_ISL_18313147 EPI_ISL_18313152
You mean G22927C
, it's branch 5 retracted from cov-lineages/pango-designation#2250 , which is less likely an artifact since more and more samples now are from labs of different countries.
Branch 44 (FLippeR) proposed cov-lineages/pango-designation#2296
After reviewing Branch 31, there are 2 outlier seqs that may be the cause of the split from HK.3
Ireland/CO-CUH-SC0333/2023|EPI_ISL_18161904|2023-08-18
Israel/ICH-741199056/2023|EPI_ISL_18300205|2023-09-14
The Irish sequence does have good coverage and it doens't seem to have S:L455F
; however the Israeli one doens't cover that area, so maybe artifact/dropout. Now that the following 24 seqs with S:L455F
(Branch 31) are placed under the EG.5.1.1 > C12020T, T24496C
branch caused by single Irish sequence, do you think it is simply HK.3 sublineage misplaced, or an actual different one? The follow-up seqs are quite Irish/English based though. @FedeGueli @AngieHinrichs
About branch 31 question: that two only sequences are a bit suspicious and this could be a well defined HK.3 sublineages. i spotted some seuqences in the tree with same nuc mutations (not all togerhter) sometimes with Orf8:A65V that is really on the top mess when popping uop in the trees.
@AngieHinrichs could you take a look please? likely excluding the two sequences listed above this branch will merge with Hk.3 resolving it.
here the tree: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_388dc_4b1290.json?f_userOrOld=uploaded%20sample
Branch 51 now has a FLippeR singlet Xinjiang/XJCDCBAZ-294/2023|EPI_ISL_18320892|2023-08-26
About branch 31 question: that two only sequences are a bit suspicious and this could be a well defined HK.3 sublineages. i spotted some seuqences in the tree with same nuc mutations (not all togerhter) sometimes with Orf8:A65V that is really on the top mess when popping uop in the trees.
As usual, there's not enough info to be really sure. I expect if I prune the two sequences, then temporarily the branch would be merged into HK.3 -- but then if they are not permanently excluded, when they are added back, I expect they would pull the branch back in because sharing 3 mutations (C12020T, T24496C, C21516T) is a parsimony win over sharing just G22927T (S:L455F).
Branch 23 reached 24 and it is spreading in Singapore while it has a branch with S:V171I spotted and proposed by @aviczhl2 I suggest to propose it.
Branch 23 reached 24 and it is spreading in Singapore while it has a branch with S:V171I spotted and proposed by @aviczhl2 I suggest to propose it.
i ve re-edited the B23 query to exclude more convergent lineages: C6541T, G21604T, G22927T, -A518G, -C1426T, -G3663A, -C5031T, -A7849G,-T16545G,-C8664T,-C3634T and now it give 20 seqs. still worth proposing it (14H-455F )
there is this EG.5.1.1 Flip tha is likely misplaced by the S:Y144F artifact: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice3_genome_test_53d56_686310.json?label=id:node_6904850
i put here a query that finds a part of it: C1471T, G22927T,T16545G and another larger that could be used to keep it checked once the tree will be fixed:C1471T, G22927T
Branch 45 seems flying
Branch 45 seems flying
Likely an italian breed. yes agree. @NkRMnZr later or tomorrow i will check every single branch i think we can add some proposal
@NkRMnZr put together please a proposal for Brnach 45 last doubling 4days very fast and going. thx @aviczhl2 for spotting.
Branch 45 now 16 intercepted also in a traveller from Germany to NY
Branch 45 proposed cov-lineages/pango-designation#2308
Branch 26 seems fast too
Branch 26 seems fast too
Please Propose it!
@NkRMnZr please propose branch 31 it is going well in Uk with a lot of samples not yet on Gisaid (27) vs 46 on Usher https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice5_genome_test_309de_f8fe00.json?label=id:node_3999349
Think that both Orf1a:L3919F and Orf1a:A656V are beneficial according to Bloom/Neher calculator.
@NkRMnZr spotted Branch 53 independently i was proposing but found here! thank you! i think T7111C, A20010T is a better query it catches 12 ( any query with defining 27571 finds 10 due to droputs) I think you can propose it it seems really fast: https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?nextcladePangoLineage=HK.3*&nucMutations1=T7111C%2CA20010T&analysisMode=CompareToBaseline& ( look at CIs distribution)
? Is the branch with S:G184S=G22112A designated elsewhere? Does not find it here yet it is 40 sequences @NkRMnZr @FedeGueli
Inquiry: C22480T,G22112A,G22927T,T4789A https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_27385_1ddad0.json?f_userOrOld=uploaded%20sample&label=id:node_1087467
? Is the branch with S:G184S=G22112A designated elsewhere? Does not find it here yet it is 40 sequences @NkRMnZr @FedeGueli
Inquiry: C22480T,G22112A,G22927T,T4789A https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_27385_1ddad0.json?f_userOrOld=uploaded%20sample&label=id:node_1087467
Yes it is branch 26 HK 11(184S)+ 455F
@nkrmnzr propose it please
South_Korea/KDCA262129/2023|EPI_ISL_18271704|2023-08-21 EG.5.1 > T26972C > C28909T > C2106A(ORF1a:T614N), A21759G(S:H66R), G22927T(S:L455F), G24004A, C25572T, G28423T(ORF9b:R47L) [Query: A18492G, G22927T, C28909T, 09/18]
This singlet grows to 6.
Please propose Branch 48 : now 24 seqs widespread inmmutliple countries with further N and S mutations https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_3b0f0_3cf480.json?c=userOrOld&label=id:node_3442179
Thank you to @krosa1910 for driving my attention on it: https://github.com/sars-cov-2-variants/lineage-proposals/issues/931
branch 7 died off, Branch 15 i would include the step deeper in the tree with
ORF1a:T2906N ( C8982A), T19710C, C27213T
cause orf8:A65V is highly unreliable.
Branch 23 is 52 now.
Transferred Branch 23 as cov-lineages/pango-designation#2319 Transferred Branch 26 as cov-lineages/pango-designation#2320 Transferred Branch 31 as cov-lineages/pango-designation#2321 Transferred Branch 33 as cov-lineages/pango-designation#2322
Transferred Branch 23 as cov-lineages/pango-designation#2319 Transferred Branch 26 as cov-lineages/pango-designation#2320 Transferred Branch 31 as cov-lineages/pango-designation#2321 Transferred Branch 33 as cov-lineages/pango-designation#2322
Thank you! great work!
this now is 4 :England/CLIMB-CM7YMX5B/2023|EPI_ISL_18227053|2023-08-27; NewZealand/23YA4860/2023|EPI_ISL_18292157|2023-09-04 and Shanghai/SCDC-FX0920-021/2023|EPI_ISL_18360191|2023-09-19 EG.5.1.1 > C11779T > C12525T(ORF1a:T4087I) > G22927T(S:L455F) [Query: C11779T, C12525T, G22927T, 3 seqs, 10/06]
Branch 48 reached 28 it seems going well still unsure if faster than HK.3: https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?nextcladePangoLineage=HK.3*&nucMutations1=G13627A%2CG22927T%2CA23539T%2CG22332G&analysisMode=CompareToBaseline&
Branch 59 is likely just misplacement i asked Angie to look at it.
Branch 46 went to 27 too. going closer to proposal threshold.
Alos branch 27 went to 31
branch 17 went to 35
branch 15 now 42 with signs of advantage in Singapore : https://cov-spectrum.org/explore/Singapore/AllSamples/Past3M/variants?nextcladePangoLineage=HK.3*&nucMutations1=C6541T%2CG22927T%2CC28087T&analysisMode=CompareToBaseline&
Branch 5 is now HK.13
Branch 39 is now HK.1.1 via https://github.com/cov-lineages/pango-designation/commit/af7949950379b6e47927b8a10d59fca5aef768c7
Branch 3 has been designated HK.14 via https://github.com/cov-lineages/pango-designation/commit/c7550b14adc5cff2e855903e3841458886c3073c
Branch 44 is now Designated JR.1.1 (EG.5.1.11.1.1) via https://github.com/cov-lineages/pango-designation/commit/bd9a2f7e2cc8baf43ae8317b9105c62673cacd63
HK.10 reaches 35 now. Should it be redesignated?
but according to Usher, only 23 are on the C19983T> G22927T branch,
S:L455F
in EG.5.1 backbone. Checking updates.C66T
,C346T
,G598A
,G1820A
,C4423T
,C6843T
,A10323G(ORF1a:K3353R)
,C12651T(ORF1a:T4129I)
,C13860T
,A15159G
,C19983T
,C22096T(S:D178D)
,C22264T(S:N234N)
,C22792T(S:I410I)
,C22998T(S:P479L)
,C26681T
,C27059T
,C27507T
,C27884T
,A29700G
Branch 1:
Transferred to main repo. Designated as HK.8
**Designated as HK.8 (EG.5.1.1.8) via cov-lineages/pango-designation@9527e15** _Transferred to cov-lineages/pango-designation#2230_ **Defining Mutations:** `EG.5.1.1` > `C11779T` > `G22927T(S:L455F)` **Query:** `C6541T, C11779T, G22927T` **Earliest seq:** 2023-06-27 (`EPI_ISL_18060870`, Yibin, Sichuan, China) **Latest seq:** 2023-07-17 (`EPI_ISL_18060877`, Zi'yang, Sichuan, China) **Sampled Countries:** China (2, Sichuan)Genomes:
`EPI_ISL_18060870, EPI_ISL_18060877`Back to Tasklist
Branch 2:
Transferred to main repo:
_Transferred to cov-lineages/pango-designation#2229_ **Defining Mutations:** `EG.5.1.1` > `C12053T(ORF1a:L3930F)` > `C503T(ORF1a:P80S)` > `C7732T, C18175T(ORF1b:P1570S), G22927T(S:L455F)` **Query:** `C503T, C6541T, G22927T` **Earliest seq:** 2023-07-15 (`EPI_ISL_18060497`, Tokyo, Japan) **Latest seq:** 2023-07-18 (`EPI_ISL_18065046`, Miyagi, Japan) **Sampled Countries:** Japan (2)Genomes:
`EPI_ISL_18060497, EPI_ISL_18065046`Back to Tasklist
Branch 3
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2194_ **Defining Mutations:** `EG.5.1.1` > `C11779T` > `C6781T, C17802T, G22927C(S:L455F)` **Query:** `C6781T, C17802T, G22927C` **Earliest seq:** 2023-07-04 (`EPI_ISL_17994488`, Shanghai, China) **Latest seq:** 2023-07-18 (`EPI_ISL_18074754`, Shanghai, China) **Sampled Countries:** China (3, Shanghai)Genomes:
`EPI_ISL_17994488, EPI_ISL_18074751, EPI_ISL_18074754`Back to Tasklist
Branch 4
Transferred to main repo
Transferred to cov-lineages/pango-designation#2224 **Defining Mutations:** `EG.5.1` > `C12100G, G22927T`(**S:L455F**) **Query:** `C12100G, G22927T` **Earliest seq:** 2023-07-09 (`EPI_ISL_18060822`, Shanghai, China) **Latest seq:** 2023-07-31 (`EPI_ISL_18094969`, Washington, USA with Travel History to: Japan) **Sampled Countries:** China (2, Shanghai, 1 ex. Thailand), USA (2, Washington, ex. Japan)Genomes:
`EPI_ISL_18060822, EPI_ISL_18075026, EPI_ISL_18094946, EPI_ISL_18094969`Back to Tasklist
Branch 5
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2250_ **Defining Mutations:** `EG.5.1.1` > `G22927C`(**S:L455F**, different to **HK.3**'s `G22927T`) **Query:** `C6541T, G22927C, -C3653T, -C6317T, -C6327T, -A6659G, -T7111C, -C8074T, -G8768A, -C10702T, -C11779T, -C13968A, -T17811C, -A21137G, -T21748C, -C22482T, -C24023T, -C27741T, -G29734T` **Earliest seq:** 2023-07-08 (`EPI_ISL_18012368`, Sichuan, China) **Latest seq:** 2023-07-27 (`EPI_ISL_18105834`, Shanghai, China) **Sampled Countries:** China (3: Shanghai/2; Sichuan/1)Genomes:
`EPI_ISL_18012368, EPI_ISL_18074450, EPI_ISL_18105834`Back to Tasklist
Branch 6
Many sequences pulled back to HK.3, the reversion probably due to dropout rather than recombinant
**Defining Mutations:** `EG.5.1.1` > _T22480C_Reversion_ > `G22927T`(**S:L455F**) **Query:** `C6541T, G13627A, G22927T, -C7948T, -C22480T` **Earliest seq:** 2023-07-05 (`EPI_ISL_17988079`, Xiangyang, Hubei) **Latest seq:** 2023-08-07 (`EPI_ISL_18105560`, Xiangyang, Hubei) **Sampled Countries:** China (4, Hubei)Genomes:
`EPI_ISL_17988079, EPI_ISL_18105559-18105560, EPI_ISL_18105562`Back to Tasklist
Branch 7
Defining Mutations:
EG.5.1.1
>C6627T(ORF1a:T2121I)
>T17147C(ORF1b:I1227T)
>G22927T
(S:L455F) Query:C6627T, T17147C, G22927T
Earliest seq: 2023-07-06 (EPI_ISL_18074610
, Shanghai) Latest seq: 2023-08-05 (EPI_ISL_18108436
, Shanghai, Travel history: Singapore) Sampled Countries: China (3: Shanghai)Genomes:
`EPI_ISL_18074610, EPI_ISL_18108436, EPI_ISL_18108490`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1999b_eabba0.json?f_userOrOld=uploaded%20sample&label=id:node_10741278
Back to Tasklist
Branch 8
Defining Mutations:
EG.5.1.1
>C5284T
>T14655C
>C15951T, G22927T
(S:L455F) Query:C5284T, T14655C, G22927T
Earliest seq: 2023-07-23 (EPI_ISL_18105571
, Shanghai) Latest seq: 2023-08-11 (EPI_ISL_18114886
, Shanghai) Sampled Countries: China (3, Shanghai)Genomes:
`EPI_ISL_18105571, EPI_ISL_18108625, EPI_ISL_18114886`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_28a92_b9eb0.json?f_userOrOld=uploaded%20sample&label=id:node_6895881
Back to Tasklist
Branch 9
Defining Mutations:
EG.5.1.1
>C19983T
>G22927T
(S:L455F) Query:C6541T, G13627A, C19983T, G22927T, -C6695T **Earliest seq:** 2023-06-30 (
EPI_ISL_18074254, Liaoning, China) **Latest seq:** 2023-08-27 (
EPI_ISL_18239976`, Utah, USA) Sampled Countries: China (3: Liaoning/2; Shanghai/1)Genomes:
`EPI_ISL_18074249, EPI_ISL_18074254`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_2cc80_bc030.json?f_userOrOld=uploaded%20sample&label=id:node_6895986
Back to Tasklist
Branch 10
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2251_ **Defining Mutations:** EG.5.1.1 > C11173T > G22927T(**S:L455F**) **Query:** `C11173T, G13627A, G22927T, -T22228C, -C27406T, -T28157C` **Earliest seq:** 2023-07-16 (`EPI_ISL_18049850`, Qinghai) **Latest seq:** 2023-08-01 (`EPI_ISL_18114762`, Shanghai) **Sampled Countries:** China (3, Qinghai, Shanghai, Xinjiang)Genomes:
`EPI_ISL_18049850, EPI_ISL_18108872, EPI_ISL_18114762`Back to Tasklist
Branch 11
Defining Mutations:
EG.5.1
>C9430T
>T1939C, C10039T, C20873G(ORF1b:A2469G), G22927T(S:L455F)
Query:C9430T, G21718T, G22927T, -C1889T, -G13627A, -C21622A
Earliest seq: 2023-07-31 (EPI_ISL_18127303
, Tokyo, Japan) Latest seq: 2023-08-07 (EPI_ISL_18127606
, Kanagawa, Japan) Sampled Countries: Japan (3: Tokyo/2; Kanagawa/1)Genomes:
`EPI_ISL_18127215, EPI_ISL_18127303, EPI_ISL_18127606`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice4_genome_1293d_792f00.json?f_userOrOld=uploaded%20sample
Back to Tasklist
Branch 12:
Designated EG.5.1.17
_Designated as **EG.5.1.17** via cov-lineages/pango-designation@5a8103c_ **Defining Mutations:** `EG.5.1` > `G22927C(S:L455F)` **Query:** `C2334T, A18492G, G22927C, -G1069A, -A22106C, -C22570T, -C25572T` **Earliest seq:** 2023-07-09 (`EPI_ISL_18108295`, Anhui, China) **Latest seq:** 2023-08-15 (`EPI_ISL_18138165`, Shanghai, China) **Sampled Countries:** China (4: Shanghai/3; Anhui/1)Genomes:
`EPI_ISL_18108295, EPI_ISL_18114797, EPI_ISL_18138165, EPI_ISL_18138282`Back to Tasklist
Branch 13:
Transferred to main repo
_transferred to cov-lineages/pango-designation#2364_ **Defining Mutations:** `EG.5.1.1` > `C19011T` > `C8991T(ORF1a:A2909V)` > `G22927T(S:L455F)` **Query:** `C8991T, C19011T, G22927T` **Earliest seq:** 2023-08-14 (`EPI_ISL_18146054`, Hubei, China) **Latest seq:** 2023-10-31 (`EPI_ISL_18473645`, Singapore, travel history: India) **Sampled Countries:** China (38: HB/23; SH/4; AH/3; BJ/2; YN/2; GS/1; HA/1; QH/1; XJ/1), Singapore (5: Local/2; ex. China/2; ex. India/1), Netherlands (3), Australia (2: NSW), Austria (1), Croatia (1), France (1), Laos (1)Genomes:
`EPI_ISL_18141179, EPI_ISL_18146054, EPI_ISL_18146087, EPI_ISL_18217222, EPI_ISL_18217236, EPI_ISL_18254205, EPI_ISL_18268148-18268149, EPI_ISL_18268153, EPI_ISL_18268244, EPI_ISL_18284712, EPI_ISL_18284755, EPI_ISL_18306934, EPI_ISL_18313098, EPI_ISL_18313105, EPI_ISL_18313198, EPI_ISL_18313226, EPI_ISL_18349877, EPI_ISL_18354962, EPI_ISL_18363349, EPI_ISL_18376465, EPI_ISL_18376494, EPI_ISL_18384477, EPI_ISL_18384508, EPI_ISL_18388887, EPI_ISL_18388889, EPI_ISL_18388891, EPI_ISL_18438085, EPI_ISL_18438311, EPI_ISL_18438356, EPI_ISL_18438359, EPI_ISL_18438427, EPI_ISL_18441693, EPI_ISL_18442727, EPI_ISL_18442730, EPI_ISL_18447747, EPI_ISL_18457659, EPI_ISL_18461703, EPI_ISL_18461971, EPI_ISL_18463327, EPI_ISL_18463426, EPI_ISL_18464919, EPI_ISL_18464984, EPI_ISL_18465193, EPI_ISL_18465381, EPI_ISL_18465391, EPI_ISL_18466345, EPI_ISL_18473414, EPI_ISL_18473645, EPI_ISL_18475163, EPI_ISL_18475178`Back to Tasklist
Branch 14
Defining Mutations:
EG.5.1.1
>A8443G
>G22927T(S:L455F)
Query:C6541T, A8443G, G22927T
Earliest seq: 2023-07-22 (EPI_ISL_18060879
Ziyang, Sichuan) Latest seq: 2023-08-09 (EPI_ISL_18146071
, Xiaogan, Hubei) Sampled Countries: China (3: Sichuan/2; Hubei/1)Genomes:
`EPI_ISL_18060879, EPI_ISL_18146071, EPI_ISL_18166195`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_140e3_db750.json?f_userOrOld=uploaded%20sample
Back to Tasklist
Branch 15
Designated with levels: HK.23, HK.23.1 and HK.23.1.1
Designated as three levels: [HK.23](https://github.com/cov-lineages/pango-designation/commit/12691b30210c9ab9b68ebfe04bda957d9a09b806), [HK.23.1](https://github.com/cov-lineages/pango-designation/commit/b83d9aa28a32b8a70a6e049b29986577cf07f23a) and [HK.23.1.1](https://github.com/cov-lineages/pango-designation/commit/b47c3ca2d6369c236951efde3b954e9ac022e5b7) _Transferred to cov-lineages/pango-designation#2340_ **Defining Mutations:** `EG.5.1.1` > `C28087T(ORF8:A65V)` > `G22927T(S:L455F)` **Query:** `C6541T, G22927T, C28087T, -A4306G, -G4444A, -A6889G, -G8171A, -T8305C, -C10039T, -C19185T, -C25207T` **Earliest seq:** 2023-08-10 (`EPI_ISL_18138246`, Shanghai) **Latest seq:** 2023-08-14 (`EPI_ISL_18208534`, Shanghai) **Sampled Countries:** China (3: Shanghai)Genomes:
`EPI_ISL_18138040, EPI_ISL_18138246, EPI_ISL_18208534`Back to Tasklist
Branch 16
Defining Mutations:
EG.5.1.1
>C8074T > T17811C
>C7604T, C10789T, C10834T, C12815T, G20348T(ORF1b:S2294I), G22927C(S:L455F), A25998G
Query:C6541T, C8074T, G22927C
Earliest seq: 2023-08-22 (EPI_ISL_18217203
, Hubei, China) Latest seq: 2023-08-22 (EPI_ISL_18217204
, Hubei, China) Sampled Countries: China (3)Genomes:
`EPI_ISL_18217202-18217204`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1c2cf_6feba0.json?c=gt-S_455&gmax=25384&gmin=21563&label=id:node_6949824
Back to Tasklist
Branch 17
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2341_ **Defining Mutations:** `EG.5.1.1` > `C9118T` > `G22927T(S:L455F)` **Query:** `C6541T, C9118T, G22927T, -C25546A` **Earliest seq:** 2023-08-14 (`EPI_ISL_18214798`, Osaka, Japan) **Latest seq:** 2023-10-02 (`EPI_ISL_18373543`, England, UK) **Sampled Countries:** Japan (37), USA (4: TX/2; NJ; SC), South Korea (2), UK (2: EN), Australia (1: WA), Canada (1: ON), France (1)Genomes:
`EPI_ISL_18162837, EPI_ISL_18166739, EPI_ISL_18214798, EPI_ISL_18214838, EPI_ISL_18226559, EPI_ISL_18235760, EPI_ISL_18236014, EPI_ISL_18242568, EPI_ISL_18243896, EPI_ISL_18247826-18247827, EPI_ISL_18253490, EPI_ISL_18261506, EPI_ISL_18271898, EPI_ISL_18279175, EPI_ISL_18279234, EPI_ISL_18285272, EPI_ISL_18285440, EPI_ISL_18294200, EPI_ISL_18300272, EPI_ISL_18338985, EPI_ISL_18342460, EPI_ISL_18354762, EPI_ISL_18354776, EPI_ISL_18362312, EPI_ISL_18370698, EPI_ISL_18370761, EPI_ISL_18371874, EPI_ISL_18372806, EPI_ISL_18373146, EPI_ISL_18373543, EPI_ISL_18376280, EPI_ISL_18376286, EPI_ISL_18377931, EPI_ISL_18382356, EPI_ISL_18382437, EPI_ISL_18382737, EPI_ISL_18385259, EPI_ISL_18387636, EPI_ISL_18390707, EPI_ISL_18390782, EPI_ISL_18390836, EPI_ISL_18397002, EPI_ISL_18402105, EPI_ISL_18402112, EPI_ISL_18411313, EPI_ISL_18413797, EPI_ISL_18413896`Back to Tasklist
Branch 18
Merged into HK.3
**Defining Mutations:** `EG.5.1.1` > `C22264T` > `G22927T(S:L455F)` **Query:** `G13627A, C22264T, G22927T` **Earliest seq:** 2023-07-30 (`EPI_ISL_18129236`, British Columbia, Canada) **Latest seq:** 2023-08-28 (`EPI_ISL_18213253`, Fujian, China) **Sampled Countries:** Canada (1, BC), China (1, Fujian), UK (1, England)Genomes:
`EPI_ISL_18129236, EPI_ISL_18142517, EPI_ISL_18213253`Back to Tasklist
Branch 19
Merged under HK.13, no longer tracking
**Defining Mutations:** `EG.5.1.1` > `C29167T` > `G1186A, T4871C(ORF1a:Y1536H), C7011T(ORF1a:A2249V), G17741A(ORF1b:R1425H), G22927C(S:L455F)` **Query:** `T4871C, G17741A` **Earliest seq:** 2023-08-09 (`EPI_ISL_18160385`, New York, USA) **Latest seq:** 2023-08-19 (`EPI_ISL_18214905`, Ibaraki, Japan) **Sampled Countries:** China (1, Shanghai), Japan (1), USA (1, NY)Genomes:
`EPI_ISL_18160385, EPI_ISL_18208589, EPI_ISL_18214905`Back to Tasklist
Branch 20
Designated as HK.33
_Designated as HK.33 via cov-lineages/pango-designation@7ad122e_ **Defining Mutations:** `EG.5.1.1` > `C2644T` > `T7957C, G22927T(S:L455F), G29348T(N:A359S)` **Query:** `C2644T, G13627A, G22927T` **Earliest seq:** 2023-08-21 (`EPI_ISL_18222131`, `SEA` airport, Washington, USA, travel history: UK) **Latest seq:** 2023-08-25 (`EPI_ISL_18208454`, Shanghai, China) **Sampled Countries:** USA (2, ex. UK), China (1, Shanghai)Genomes:
`EPI_ISL_18147035, EPI_ISL_18208454, EPI_ISL_18222131`Back to Tasklist
Branch 21, now pulled under HK.3.8
Pulled under HK.3.8
**Defining Mutations:** `EG.5.1.1` > `C18747T` > `C643T, T13060C, G19723T(ORF1b:V2086F), G22927T(S:L455F)` **Query:** `C643T, C18747T, G22927T` **Earliest seq:** 2023-08-11 (`EPI_ISL_18208543`, Shanghai) **Latest seq:** 2023-08-28 (`EPI_ISL_18232547`, Shanghai Customs, travel history to Japan **Sampled Countries:** China (3, SH)Genomes:
`EPI_ISL_18208543, EPI_ISL_18208548, EPI_ISL_18232547`Back to Tasklist
Branch 22, Now pulled under
HK.3.2
>A708C(ORF1a:E148A)
>C10969T, G23593T(S:Q677H), G28056A(ORF8:A55T)
, no longer tracking.Pulled under HK.3.2
**Defining Mutations:** `HK.5` > `G22927T(S:L455F)` **Query:** `spike_Q52H, spike_L455F, spike_Q677H` **Earliest seq:** 2023-08-13 (`EPI_ISL_18146068`, Hubei) **Latest seq:** 2023-08-24 (`EPI_ISL_18226161`, Virginia) **Sampled Countries:** USA (2, VA), China (1, HB)Genomes:
`EPI_ISL_18146068, EPI_ISL_18226161-18226162`Back to Tasklist
Branch 23
Transferred to main repo:
_Transferred to main repo cov-lineages/pango-designation#2319_ **Defining Mutations:** `HK.2` > `G22927T(S:L455F)` **Query:** `C6541T, G21604T, G22927T, -A518G, -C934T, -C1426T, -G3663A, -C5031T, -C7712T, -A7849G, -C8320T, -T16545G` **Earliest seq:** 2023-08-21 (`EPI_ISL_18141161`, Singapore) **Latest seq:** 2023-08-23 (`EPI_ISL_18232599`, Shanghai) **Sampled Countries:** Singapore (1), China (2, SH)Genomes:
`EPI_ISL_18141161, EPI_ISL_18232598-18232599`Back to Tasklist
Branch 24, Designated as
HK.20
via cov-lineages/pango-designation@71cf97b ; follow-upS:G482R/G23006C
designated asHK.20.1
Designated as HK.20 and HK.20.1
_Transferred to cov-lineages/pango-designation#2353_ **Defining Mutations:** `EG.5.1.1` > `C6695T(ORF1a:P2144S)` > `C9448A` > `C5575T, G22927T(S:L455F)` **Query:** `C6695T, C9448A, G22927T` **Earliest seq:** 2023-08-13 (`EPI_ISL_18114870`, Shanghai Customs, travel history to Japan) **Latest seq:** 2023-10-20 (`EPI_ISL_18448529`, Ontario, Canada) **Sampled Countries:** China (13, SH/6; SC/4; FJ/1; ex. Japan/1; ex. S. Korea/1), USA (12: CA/8; AZ/1; OH/1; TX/1; ex. Nepal/1), Singapore (6: Local/5; ex. China/1), Italy (5), UK (3: EN), Australia (2: NSW; QLD), Canada (2: ON), Japan (2), South Korea (2), Switzerland (2), Denmark (1), France (1), Spain (1)Genomes:
`EPI_ISL_18114870, EPI_ISL_18208555, EPI_ISL_18208592, EPI_ISL_18208601, EPI_ISL_18232643, EPI_ISL_18246292, EPI_ISL_18284706, EPI_ISL_18285031, EPI_ISL_18285192, EPI_ISL_18306956, EPI_ISL_18307066, EPI_ISL_18320793, EPI_ISL_18328004, EPI_ISL_18352555, EPI_ISL_18354001, EPI_ISL_18355023, EPI_ISL_18360344, EPI_ISL_18360616, EPI_ISL_18361723, EPI_ISL_18366403, EPI_ISL_18370066, EPI_ISL_18370200, EPI_ISL_18371411, EPI_ISL_18376528, EPI_ISL_18385607, EPI_ISL_18386446, EPI_ISL_18386489, EPI_ISL_18387133, EPI_ISL_18397207, EPI_ISL_18403093, EPI_ISL_18407761, EPI_ISL_18409112, EPI_ISL_18411495, EPI_ISL_18415804, EPI_ISL_18421982, EPI_ISL_18423702, EPI_ISL_18425050, EPI_ISL_18428715, EPI_ISL_18429030, EPI_ISL_18430106, EPI_ISL_18433978, EPI_ISL_18435244, EPI_ISL_18442967, EPI_ISL_18443714, EPI_ISL_18443742-18443744, EPI_ISL_18443746, EPI_ISL_18444154, EPI_ISL_18446641, EPI_ISL_18448416, EPI_ISL_18448529`Back to Tasklist
Branch 25: Mostly with
S:A684V
Defining Mutations: EG.5.1.1 >
C29296T
>G22927T(S:L455F)
Query:C6541T, G22927T, C29296T
Earliest seq: 2023-08-06 (EPI_ISL_18133933
, Qinghai) Latest seq: 2023-08-30 (EPI_ISL_18245873
, Gansu) Sampled Countries: China (4: SC/2; GS; QH)Genomes:
`EPI_ISL_18133933, EPI_ISL_18245873, EPI_ISL_18246316, EPI_ISL_18246328`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_fec3_1b4b0.json?label=id:node_10825408
Back to Tasklist
Branch 26
Transferred to main repo
_Transferred to main repo cov-lineages/pango-designation#2320_ **Defining Mutations:** `HK.11` > `T13228C` > `T4789A` > `G22927T(S:L455F)` **Query:** `T4789A, T13228C, G22927T` **Earliest seq:** 2023-08-21 (`EPI_ISL_18221467`, Halland, Sweden) **Latest seq:** 2023-08-21 (`EPI_ISL_18244247`, Denmark) **Sampled Countries:** Denmark (2), Sweden (1)Genomes:
`EPI_ISL_18221467, EPI_ISL_18244233, EPI_ISL_18244247`Back to Tasklist
Branch 27
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2342_ **Defining Mutations:** `EG.5.1.1` > `C25493A(ORF3a:T34K)` > `G28884C(N:G204P)` > `G22927T(S:L455F)` **Query:** `C6541T, G22927T, C25493A` **Earliest seq:** 2023-07-18 (`EPI_ISL_18245992`, Heilongjiang) **Latest seq:** 2023-10-10 (`EPI_ISL_18397223`, Singapore) **Sampled Countries:** China (18: HL/10; LN/2; SH/2; HB; SC; SX; YN), Singapore (14), Denmark (4), Italy (3), USA (3: CA/2; NY), France (2), Australia (1: NSW), Germany (1), South Korea (1), Sweden (1)Genomes:
`EPI_ISL_18138073, EPI_ISL_18232576, EPI_ISL_18244264, EPI_ISL_18245964, EPI_ISL_18245971, EPI_ISL_18245992, EPI_ISL_18246139, EPI_ISL_18246193, EPI_ISL_18282065, EPI_ISL_18300796, EPI_ISL_18306948, EPI_ISL_18306976, EPI_ISL_18306993, EPI_ISL_18307005-18307006, EPI_ISL_18307019, EPI_ISL_18307026, EPI_ISL_18313136, EPI_ISL_18320696, EPI_ISL_18324230, EPI_ISL_18329168, EPI_ISL_18330265, EPI_ISL_18339790, EPI_ISL_18352920, EPI_ISL_18356975, EPI_ISL_18361976, EPI_ISL_18362045, EPI_ISL_18376532, EPI_ISL_18376955, EPI_ISL_18377536, EPI_ISL_18377636, EPI_ISL_18382895, EPI_ISL_18384393, EPI_ISL_18384413, EPI_ISL_18384418, EPI_ISL_18384426, EPI_ISL_18384448, EPI_ISL_18384625, EPI_ISL_18384643, EPI_ISL_18391206-18391207, EPI_ISL_18397223, EPI_ISL_18397241, EPI_ISL_18397267, EPI_ISL_18397584, EPI_ISL_18401938, EPI_ISL_18405209, EPI_ISL_18406218`Back to Tasklist
Branch 28
Transferred to main repo:
_Transferred to cov-lineages/pango-designation#2398_ **Defining Mutations:** **EG.5.1.1** > `C5812T` > `G22927T(S:L455F)`, mostly with >> `A26565C(M:K15Q), C28770G(N:T166R)` **Query:** `C5812T, G22927T, C28770G` (for major `A26565C(M:K15Q), C28770G(N:T166R)` sub-branch only) **Earliest seq:** 2023-08-09 (`EPI_ISL_18214077`, South Korea) **Latest seq:** 2023-11-09 (`EPI_ISL_18547984`, Nevada, USA) **Sampled Countries:** South Korea (68), USA (5: NV/2; NC/1; ex. S. Korea/2), Australia (2: NSW; QLD), China (2: SC/1; ex. S. Korea/1), Denmark (2), Hungary (2), Finland (1), Japan (1)Genomes:
`EPI_ISL_18214077, EPI_ISL_18236938, EPI_ISL_18293068, EPI_ISL_18293497, EPI_ISL_18347905, EPI_ISL_18353940, EPI_ISL_18354370, EPI_ISL_18354403, EPI_ISL_18355265, EPI_ISL_18355547, EPI_ISL_18368528, EPI_ISL_18382157, EPI_ISL_18382304, EPI_ISL_18382505, EPI_ISL_18382615, EPI_ISL_18386641, EPI_ISL_18408701-18408702, EPI_ISL_18408814, EPI_ISL_18408878, EPI_ISL_18411301, EPI_ISL_18415920, EPI_ISL_18435710, EPI_ISL_18438964, EPI_ISL_18439203, EPI_ISL_18439262-18439263, EPI_ISL_18439368, EPI_ISL_18439436, EPI_ISL_18460639, EPI_ISL_18460726, EPI_ISL_18460826, EPI_ISL_18461023, EPI_ISL_18461030, EPI_ISL_18461109, EPI_ISL_18461117, EPI_ISL_18461139, EPI_ISL_18488790, EPI_ISL_18488878, EPI_ISL_18488904, EPI_ISL_18489119, EPI_ISL_18501908, EPI_ISL_18502007, EPI_ISL_18503617, EPI_ISL_18503624, EPI_ISL_18503755, EPI_ISL_18503952, EPI_ISL_18503974, EPI_ISL_18511170, EPI_ISL_18511222, EPI_ISL_18511248, EPI_ISL_18511257, EPI_ISL_18511484, EPI_ISL_18513699, EPI_ISL_18518361, EPI_ISL_18535616, EPI_ISL_18535618, EPI_ISL_18535641, EPI_ISL_18535643-18535644, EPI_ISL_18535683, EPI_ISL_18539076, EPI_ISL_18539319, EPI_ISL_18539641, EPI_ISL_18539827, EPI_ISL_18540358, EPI_ISL_18544082, EPI_ISL_18547609, EPI_ISL_18547984, EPI_ISL_18550336, EPI_ISL_18552522, EPI_ISL_18559930, EPI_ISL_18564453, EPI_ISL_18564477, EPI_ISL_18564533, EPI_ISL_18564565, EPI_ISL_18564603, EPI_ISL_18564701, EPI_ISL_18564813, EPI_ISL_18564892, EPI_ISL_18564897, EPI_ISL_18565136`Back to Tasklist
Branch 29
Now pulled under HK.3
**Defining Mutations:** **EG.5.1.1** > `C16726T(ORF1b:H1087Y)` > `G9424T, A12472G, G22927T(S:L455F), T23030C(**S:F490P**), G27621T(ORF7a:Q76H)` **Query:** `A12472G, G22927T, G27621T` **Earliest seq:** 2023-08-25 (`EPI_ISL_18245860`, Fujian, China) **Latest seq:** 2023-09-06 (`EPI_ISL_18243501`, Singapore) **Sampled Countries:** Singapore (2), China (1, FJ)Genomes:
`EPI_ISL_18243491, EPI_ISL_18243501, EPI_ISL_18245860`Back to Tasklist
Branch 30
Now pulled under HK.3
**Defining Mutations:** **EG.5.1.1** > `C4423T` > `G22927T(S:L455F)` **Query:** `C4423T, G13627A, G22927T` **Earliest seq:** 2023-08-12 (`EPI_ISL_18246284`, Sichuan, China) **Latest seq:** 2023-08-25 (`EPI_ISL_18235973`, Chiba, Japan) **Sampled Countries:** China (2, SC), Japan (1)Genomes:
`EPI_ISL_18232772, EPI_ISL_18235973, EPI_ISL_18246284`Back to Tasklist
Branch 31
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2321_ **Defining Mutations:** **EG.5.1.1** > `C12020T(ORF1a:L3919F), T24496C` > `C2232T(ORF1a:A656V), C21516T, G22927T(S:L455F)` **Query:** `C6541T, C12020T, G22927T, -G6337T, -C8982A, -G18445A, -C28087T` **Earliest seq:** 2023-08-21 (`EPI_ISL_18216560`, Galway, Ireland) **Latest seq:** 2023-09-04 (`EPI_ISL_18254216`, Hubei) **Sampled Countries:** China (1), Ireland (1), UK (1)Genomes:
`EPI_ISL_18216560, EPI_ISL_18244531, EPI_ISL_18254216`Back to Tasklist
Branch 32
Defining Mutations: EG.5.1.1 >
T4579A
>G2329A, A8443G
>G22927T(S:L455F)
Query:T4579A, A8443G, G22927T
Earliest seq: 2023-08-08 (EPI_ISL_18166186
, Sichuan) Latest seq: 2023-08-26 (EPI_ISL_18254268
, Hubei) Sampled Countries: China (5)Genomes:
`EPI_ISL_18166186, EPI_ISL_18232746, EPI_ISL_18245861, EPI_ISL_18246325, EPI_ISL_18254268`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_647e_1a2900.json?label=id:node_6956460
Back to Tasklist
Branch 33
Designated as EG.5.1.19
_Designated as **EG.5.1.19** via cov-lineages/pango-designation@0807c23 , after transferred to cov-lineages/pango-designation#2322_ **Defining Mutations:** **EG.5.1** > `T26171A(ORF3a:M260K)` > `A17615G(ORF1b:K1383R), G22927T(S:L455F)` **Query:** `G21718T, G22927T, T26171A` **Earliest seq:** 2023-08-09 (`EPI_ISL_18134871`, Daknam, Belgium) **Latest seq:** 2023-09-03 (`EPI_ISL_18252041`, `SEA` airport, Washington, with travel hisotry: Netherlands) **Sampled Countries:** Belgium (1), France (1), Romania (1), USA (1, ex. Netherlands)Genomes:
`EPI_ISL_18134871, EPI_ISL_18229094, EPI_ISL_18252041, EPI_ISL_18254718`Back to Tasklist
Branch 34, NOT FLip but with
S:L455S
Defining Mutations: EG.5.1.3 >
G2946A(ORF1a:G894D), T15264C, T22926C(S:L455S)
Query:C1889T, C2334T, T22926C, -A4340G, -A10703C
Earliest seq: 2023-07-27 (EPI_ISL_18248425
, Zagreb, Croatia) Latest seq: 2023-07-31 (EPI_ISL_18248430
, Zagreb, Croatia) Sampled Countries: Croatia (4)Genomes:
`EPI_ISL_18248425, EPI_ISL_18248427, EPI_ISL_18248429-18248430`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1ed45_24dab0.json?f_userOrOld=uploaded%20sample&label=id:node_10831638
Back to Tasklist
Branch 35, side-branch to JJ.1
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2354_ **Defining Mutations:** **EG.5.1.4** > `C26111T(ORF3:P240L)` > `C18555T` > `T17268C` > `G22927T(S:L455F)` **Query:** `T17268C, G22927T, C26111T` **Earliest seq:** 2023-08-08 (`EPI_ISL_18132133`, Newfoundland and Labrador) **Latest seq:** 2023-10-23 (`EPI_ISL_18448815`, Ontario, Canada) **Sampled Countries:** Canada (49: ON/22; NL/15; AB/10; BC/1; NS/1), US (7: CA/2; NY/2; AZ/1; UT/1; VA/1), France (1)Genomes:
`EPI_ISL_18132133, EPI_ISL_18256806, EPI_ISL_18258767, EPI_ISL_18258769-18258770, EPI_ISL_18258773, EPI_ISL_18258778, EPI_ISL_18291996, EPI_ISL_18291998, EPI_ISL_18292017, EPI_ISL_18292020-18292022, EPI_ISL_18292026-18292028, EPI_ISL_18333999, EPI_ISL_18344763, EPI_ISL_18357035, EPI_ISL_18372328, EPI_ISL_18372367, EPI_ISL_18383112, EPI_ISL_18383123-18383124, EPI_ISL_18383697, EPI_ISL_18388693, EPI_ISL_18395288, EPI_ISL_18395414, EPI_ISL_18395581, EPI_ISL_18404467, EPI_ISL_18425010, EPI_ISL_18425420, EPI_ISL_18425431, EPI_ISL_18425847, EPI_ISL_18425967, EPI_ISL_18426727, EPI_ISL_18427300, EPI_ISL_18427492, EPI_ISL_18427494, EPI_ISL_18427496, EPI_ISL_18427507, EPI_ISL_18427602, EPI_ISL_18431345, EPI_ISL_18436820, EPI_ISL_18437028, EPI_ISL_18437176, EPI_ISL_18438632, EPI_ISL_18438777, EPI_ISL_18448237, EPI_ISL_18448584-18448585, EPI_ISL_18448588, EPI_ISL_18448699-18448700, EPI_ISL_18448702, EPI_ISL_18448740, EPI_ISL_18448815`Back to Tasklist
Branch 36
Transferred to main repo:
_Transferred to cov-lineages/pango-designation#2399_ **Defining Mutations:** **EG.5.1.1** > `C22388T(S:L276L)` > `G22927T(S:L455F)`, mostly with >> `C1853T` sub-branch **Query:** `C1853T, G13627A, G22927T, -C4780T, -C5031T, -C6627T, -C8982A` (for major `C1853T` sub-branch only) **Earliest seq:** 2023-08-14 (`EPI_ISL_18224087`, Colorado, USA) **Latest seq:** 2023-11-20 (`EPI_ISL_18568071`, `SEA` airport, travel history: France) **Sampled Countries:** France (20), Norway (12), Germany (11), Switzerland (8), USA (6: CO/2; ex. France/2; ex.Germany/2), UK (4: EN), China (3: XJ/2; FJ/1), Denmark (3), Ukraine (3), Canada (2: NB; ON), Finland (2), Spain (2), Belgium (1), Italy (1), Japan (1), Singapore (1)Genomes:
`EPI_ISL_18224087, EPI_ISL_18224096, EPI_ISL_18233134, EPI_ISL_18239749, EPI_ISL_18263561, EPI_ISL_18263571, EPI_ISL_18263574, EPI_ISL_18263576, EPI_ISL_18272601-18272602, EPI_ISL_18280654, EPI_ISL_18280813, EPI_ISL_18290994, EPI_ISL_18291008, EPI_ISL_18291011, EPI_ISL_18308259, EPI_ISL_18313749, EPI_ISL_18326424, EPI_ISL_18326608, EPI_ISL_18327645, EPI_ISL_18337648, EPI_ISL_18337651, EPI_ISL_18338378, EPI_ISL_18373487, EPI_ISL_18373856, EPI_ISL_18380089, EPI_ISL_18380091, EPI_ISL_18388662, EPI_ISL_18388711, EPI_ISL_18411952, EPI_ISL_18412072, EPI_ISL_18421745, EPI_ISL_18421949, EPI_ISL_18428144, EPI_ISL_18428460, EPI_ISL_18428992, EPI_ISL_18433011, EPI_ISL_18441991, EPI_ISL_18451507, EPI_ISL_18464584, EPI_ISL_18464947, EPI_ISL_18468968, EPI_ISL_18476770, EPI_ISL_18485554, EPI_ISL_18486361, EPI_ISL_18486756, EPI_ISL_18493947, EPI_ISL_18494748, EPI_ISL_18495920, EPI_ISL_18496297, EPI_ISL_18496628, EPI_ISL_18496636, EPI_ISL_18496703, EPI_ISL_18499460, EPI_ISL_18505686, EPI_ISL_18505750, EPI_ISL_18519177-18519178, EPI_ISL_18525816, EPI_ISL_18530654, EPI_ISL_18530657-18530658, EPI_ISL_18530757, EPI_ISL_18530938, EPI_ISL_18530967, EPI_ISL_18538000, EPI_ISL_18540615, EPI_ISL_18540768, EPI_ISL_18540871, EPI_ISL_18540915, EPI_ISL_18544152, EPI_ISL_18552615, EPI_ISL_18553571, EPI_ISL_18556840, EPI_ISL_18568060, EPI_ISL_18568071, EPI_ISL_18568733-18568735, EPI_ISL_18570228`Back to Tasklist
Branch 37
⚠
C29095T
became homoplastic across the EG.5.1+L455F tree, no longer tracking.No longer tracking
**Defining Mutations:** **EG.5.1.1** > `C29095T` > `G22927T(S:L455F)` **Query:** `G13627A, G22927T, C29095T` **Earliest seq:** 2023-08-28 (`EPI_ISL_18246374`, Sichuan, China) **Latest seq:** 2023-08-31 (`EPI_ISL_18264700`, Texas, USA) **Sampled Countries:** USA (2: TX), China (1: SC)Genomes:
`EPI_ISL_18246374, EPI_ISL_18264482, EPI_ISL_18264700`Back to Tasklist
Branch 38
Defining Mutations: EG.5.1.1 >
T24583C
>G22927T(S:L455F)
Query:C6541T, G22927T, T24583C
Earliest seq: 2023-08-03 (EPI_ISL_18166149
, Sichuan) Latest seq: 2023-08-26 (EPI_ISL_18268462
Shanghai) Sampled Countries: China (3: SC/2; SH/1)Genomes:
`EPI_ISL_18166149, EPI_ISL_18232692, EPI_ISL_18268462`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_f9a8_5a58c0.json?f_userOrOld=uploaded%20sample&label=id:node_10885352
Back to Tasklist
Branch 39
Defining Mutations: HK.1 (EG.5.1.1.1) >
G22927T(S:L455F)
Query:C6541T, G13627A, G22332T, G22927T
+C6541T, G13627A, G22332A, G22927T
Earliest seq: 2023-08-09 (EPI_ISL_18146086
, Hubei) Latest seq: 2023-08-28 (EPI_ISL_18254226
, Hubei) Sampled Countries: China (7)Genomes:
`EPI_ISL_18146086, EPI_ISL_18146100, EPI_ISL_18254226-18254227, EPI_ISL_18268425, EPI_ISL_18138066, EPI_ISL_18254258`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1cca6_5afd40.json?f_userOrOld=uploaded%20sample&label=id:node_6971951
Back to Tasklist
Branch 40
Defining Mutations: EG.5.1.1 >
C10615T
>G22927T(S:L455F)
>C1426T, G25691T(ORF3a:G100V)
Query:C1426T, C10615T, G22927T
Earliest seq: 2023-08-08 (EPI_ISL_18138249
, Shanghai) Latest seq: 2023-08-25 (EPI_ISL_18268441
, Shanghai) Sampled Countries: China (4: SH)Genomes:
`EPI_ISL_18138249, EPI_ISL_18208636, EPI_ISL_18268441, EPI_ISL_18268482`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_20010_5b23f0.json?f_userOrOld=uploaded%20sample&label=id:node_6983332
Back to Tasklist
Branch 41
Defining Mutations: EG.5.1.1 >
C24023T
>C2485T, G15025A(ORF1b:A520T), G22927C(S:L455F)
Query:C6541T, G22927C, C24023T
Earliest seq: 2023-08-14 (EPI_ISL_18239206
, South Korea) Latest seq: 2023-08-24 (EPI_ISL_18254859
, South Korea) Sampled Countries: South Korea (3)Genomes:
`EPI_ISL_18239206, EPI_ISL_18254859, EPI_ISL_18271926`UShER: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_26c10_8252f0.json?f_userOrOld=uploaded%20sample&label=id:node_10885690
Back to Tasklist
Branch 42
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2355_ **Defining Mutations:** **EG.5.1.1** > `C22687T` > `G22927T(S:L455F)` **Query:** `C6541T, C22687T, G22927T, -T2145C, -A16482C, -C21191T` **Earliest seq:** 2023-08-14 (`EPI_ISL_18279039`, Singapore, travel history: China) **Latest seq:** 2023-09-01 (`EPI_ISL_18278560`, Alberta, Canada) **Sampled Countries:** China (21: GS/4; HB/3; XJ/3; AH/2; SC/2; SX/2; FJ/1; HK/1; QH/1; SH/1; YN/1), Australia (12: NSW/5; SA/4; QLD/1; TA/1; VIC/1), South Korea (8), Canada (6: AB), USA (3: AZ/1; ex. Australia/2), Singapore (2: Local/1; ex. China/1), Japan (1)Genomes:
`EPI_ISL_18146046, EPI_ISL_18213336, EPI_ISL_18217223, EPI_ISL_18278558, EPI_ISL_18278560, EPI_ISL_18279039, EPI_ISL_18289881, EPI_ISL_18293677, EPI_ISL_18293698, EPI_ISL_18311984, EPI_ISL_18312274, EPI_ISL_18312380, EPI_ISL_18313209, EPI_ISL_18327623, EPI_ISL_18327666, EPI_ISL_18346251, EPI_ISL_18346325, EPI_ISL_18347707, EPI_ISL_18350428, EPI_ISL_18360224, EPI_ISL_18361336, EPI_ISL_18361999, EPI_ISL_18365676, EPI_ISL_18365684, EPI_ISL_18365890, EPI_ISL_18366374, EPI_ISL_18382081, EPI_ISL_18382589, EPI_ISL_18382710, EPI_ISL_18384562, EPI_ISL_18388967, EPI_ISL_18389014, EPI_ISL_18389016, EPI_ISL_18390872, EPI_ISL_18396110, EPI_ISL_18401894, EPI_ISL_18401903, EPI_ISL_18401983, EPI_ISL_18404054, EPI_ISL_18408752, EPI_ISL_18411422, EPI_ISL_18411665, EPI_ISL_18411717, EPI_ISL_18411753, EPI_ISL_18425089, EPI_ISL_18427884, EPI_ISL_18435235, EPI_ISL_18438336, EPI_ISL_18438338, EPI_ISL_18438347, EPI_ISL_18439100, EPI_ISL_18447517, EPI_ISL_18447771`Back to Tasklist
Branch 43
now seems to be pulled under HK.3, no longer tracking
Pulled under HK.3
**Defining Mutations:** **EG.5.1.1** > `C19524T` > `G22927T(S:L455F), A28254Δ` **Query:** `G13627A, C19524T, G22927T, -C5031T` **Earliest seq:** 2023-08-19 (`EPI_ISL_18246322`, Sichuan) **Latest seq:** 2023-09-07 (`EPI_ISL_18277156`, Fujian) **Sampled Countries:** China (3: FJ; HL; SC)Genomes:
`EPI_ISL_18246049, EPI_ISL_18246322, EPI_ISL_18277156`Back to Tasklist
Branch 44, "FLippeR"
Transferred to main Repo
_Transferred to cov-lineages/pango-designation#2296_ **Defining Mutations:** **EG.5.1** > `A22106C(S:K182Q)` > `C22995G(S:T478R), A25664G(ORF3a:Y91C)` > `C1613T(ORF1a:L450F), G20995T(ORF1b:G2510C), G22927C(S:L455F), C25803T, A27388C` **Query:** `A22106C, G22927C, C22995G` **Earliest seq:** 2023-08-14 (`EPI_ISL_18160020`, Denmark, or, `EPI_ISL_18278998`, Singapore) **Latest seq:** 2023-09-04 (`EPI_ISL_18243476`, Singapore) **Sampled Countries:** Singapore (2), Denmark (1)Genomes:
`EPI_ISL_18160020, EPI_ISL_18243476, EPI_ISL_18278998`Back to Tasklist
Branch 45
Transferred to main Repo
_Transferred to cov-lineages/pango-designation#2308_ **Defining Mutations:** `EG.5.1.1` > `C13968A, A15885G` > `T11449C` > `C10369T, G22927T(S:L455F), C29077T, G29140T(N:Q289H)` **Query:** `T11449C, C13968A, G22927T` **Earliest seq:** 2023-09-06 (`EPI_ISL_18273676`, England) **Latest seq:** 2023-09-07 (`EPI_ISL_18284457`, `IAD` Airport, DC, travel history: Italy) **Sampled Countries:** UK (2: EN) USA (2, ex. Italy)Genomes:
`EPI_ISL_18273676, EPI_ISL_18281373, EPI_ISL_18284072, EPI_ISL_18284457`Back to Tasklist
Branch 46 with a sub-lineage of
S:L452Q
, designated as HK.22parental lineage of HK.22
_Branch 46 + S:L452Q designated as HK.22 via cov-lineages/pango-designation@2d3115a_ **Defining Mutations:** `EG.5.1.1` > `G25407T(ORF3a:M5I)` > `C2662T` > `G22927T(S:L455F)` **Query:** `C2662T, G22927T, G25407T` **Earliest seq:** 2023-08-06 (`EPI_ISL_18114750`, Shanghai) **Latest seq:** 2023-09-06 (`EPI_ISL_18284970`, Shanghai) **Sampled Countries:** China (4: SH)Genomes:
`EPI_ISL_18114750, EPI_ISL_18232688, EPI_ISL_18284888, EPI_ISL_18284970`Back to Tasklist
Branch 47
Defining Mutations:
EG.5.1.1
>C7600T
>G22927T(S:L455F)
>T10216C
Query:C7600T, T10216C, G22927T
Earliest seq: 2023-08-22 (EPI_ISL_18246331
, Sichuan) Latest seq: 2023-09-04 (EPI_ISL_18284731
, Hubei) Sampled Countries: China (5)Genomes:
`EPI_ISL_18246331, EPI_ISL_18284731, EPI_ISL_18284776, EPI_ISL_18284783, EPI_ISL_18284960`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3ad47_b108e0.json?f_userOrOld=uploaded%20sample&label=id:node_10899080
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Branch 48
Transferred to main repo
Transferred to cov-lineages/pango-designation#2360 ⚠️ Please check potential misplacement. **Defining Mutations:** `EG.5.1.1` > `A23539T(S:S659S)` > `G22927T(S:L455F)` **Query:** `G13627A, G22927T, A23539T, -T899C, -C2662T, -C10015T, -T12865C, -G22332A` **Earliest seq:** 2023-08-16 (`EPI_ISL_18141107`, Singapore) **Latest seq:** 2023-10-22 (`EPI_ISL_18440472`, Netherlands) **Sampled Countries:** Australia (32: NSW/14; SA/8; QLD/4; VIC/3; TAS/1; WA/1), China (10: SC/4; HB/2; SH/2; FJ/1; XJ/1), New Zealand (9), Singapore (4), Netherlands (3), USA (2), France (1)Genomes:
`EPI_ISL_18141107, EPI_ISL_18246326, EPI_ISL_18278997, EPI_ISL_18279955, EPI_ISL_18292475, EPI_ISL_18300669, EPI_ISL_18307132, EPI_ISL_18320781, EPI_ISL_18324527, EPI_ISL_18324537, EPI_ISL_18324951, EPI_ISL_18346779, EPI_ISL_18346805, EPI_ISL_18346818, EPI_ISL_18347516, EPI_ISL_18347639, EPI_ISL_18347703-18347704, EPI_ISL_18347710, EPI_ISL_18352381, EPI_ISL_18355046, EPI_ISL_18360352, EPI_ISL_18365605, EPI_ISL_18365672, EPI_ISL_18365874, EPI_ISL_18376439, EPI_ISL_18388898, EPI_ISL_18396188, EPI_ISL_18411419, EPI_ISL_18411467, EPI_ISL_18411551, EPI_ISL_18411564, EPI_ISL_18411674, EPI_ISL_18411695, EPI_ISL_18423924, EPI_ISL_18427871, EPI_ISL_18428112, EPI_ISL_18435043, EPI_ISL_18438373, EPI_ISL_18440466, EPI_ISL_18440472, EPI_ISL_18440476, EPI_ISL_18442757, EPI_ISL_18442774, EPI_ISL_18447732, EPI_ISL_18454463, EPI_ISL_18454489, EPI_ISL_18457508, EPI_ISL_18459380, EPI_ISL_18459604, EPI_ISL_18459721, EPI_ISL_18459855, EPI_ISL_18459912, EPI_ISL_18459940, EPI_ISL_18461585, EPI_ISL_18461782, EPI_ISL_18461792, EPI_ISL_18461895, EPI_ISL_18461916, EPI_ISL_18461956, EPI_ISL_18464115`Back to Tasklist
Branch 49
Now at least 3 smaller clusters seems pulled together a
S:L455F
branch right under EG.5.1.4 polytomy, hard to catch by proper query now.Query failed
**Defining Mutations:** `EG.5.1.4` > `C8407T, C11008A(ORF1a:H3581Q), G22927T(S:L455F), G25538T(ORF3a:G49V), C25572T` **Query:** `A18492G, A21137G, G22927T, -C6120T, -G13627A, -C26111T` **Earliest seq:** 2023-08-21 (`EPI_ISL_18284756`, Hubei) **Latest seq:** 2023-09-03 (`EPI_ISL_18284729`, Hubei) **Sampled Countries:** China (3)Genomes:
`EPI_ISL_18284721, EPI_ISL_18284729, EPI_ISL_18284756`Back to Tasklist
Branch 50
Defining Mutations:
EG.5.1.1
>G28904T(N:A211S)
>G22927T(S:L455F), G27261T, C28744T
Query:C6541T, G22927T, G28904T
Earliest seq: 2023-08-30 (EPI_ISL_18268410
, Shanghai) Latest seq: 2023-09-03 (EPI_ISL_18254255
, Hubei) Sampled Countries: China (5)Genomes:
`EPI_ISL_18254255, EPI_ISL_18268410, EPI_ISL_18289864, EPI_ISL_18289874, EPI_ISL_18289889`UShER: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_523af_c118f0.json?f_userOrOld=uploaded%20sample&label=id:node_6955662
Back to Tasklist
Branch 51
Transferred to main repo
_transferred to cov-lineages/pango-designation#2365_ **Defining Mutations:** EG.5.1.1 > `C10015T` > `G22927T(S:L455F)` **Query:** `C6541T, C10015T, G22927T, -C4586T` **Earliest seq:** 2023-07-31 (`EPI_ISL_18246153`, Heilongjiang) **Latest seq:** 2023-10-31 (`EPI_ISL_18473950`, Spain) **Sampled Countries:** China (20: SH/6; HL/5; LN/3; AH/1; BJ/1; GS/1; HB/1; SC/1; SX/1; XJ/1), Canada (10: ON/9; NS/1), Australia (5: NSW/4; QLD/1), Singapore (5), Spain (5), Croatia (4), USA (3: NY/2; HI/1), Denmark (2), Japan (2), Belgium (1), France (1), Italy (1), Switzerland (1)Genomes:
`EPI_ISL_18246153, EPI_ISL_18268220, EPI_ISL_18284760, EPI_ISL_18289806, EPI_ISL_18304238, EPI_ISL_18307185, EPI_ISL_18309728, EPI_ISL_18320892, EPI_ISL_18333882, EPI_ISL_18354453, EPI_ISL_18356455, EPI_ISL_18362071, EPI_ISL_18382338, EPI_ISL_18384364, EPI_ISL_18388937, EPI_ISL_18388943, EPI_ISL_18392626, EPI_ISL_18392641, EPI_ISL_18395616, EPI_ISL_18398918, EPI_ISL_18401900, EPI_ISL_18422863, EPI_ISL_18425076, EPI_ISL_18433557, EPI_ISL_18438020, EPI_ISL_18438314, EPI_ISL_18438838, EPI_ISL_18445101, EPI_ISL_18445501, EPI_ISL_18446144, EPI_ISL_18448315, EPI_ISL_18448907-18448908, EPI_ISL_18448913-18448914, EPI_ISL_18461557, EPI_ISL_18461608, EPI_ISL_18461684, EPI_ISL_18461722, EPI_ISL_18464481, EPI_ISL_18464633, EPI_ISL_18465094, EPI_ISL_18465113, EPI_ISL_18465171, EPI_ISL_18465395, EPI_ISL_18465403, EPI_ISL_18466062, EPI_ISL_18466326-18466327, EPI_ISL_18466420, EPI_ISL_18466590, EPI_ISL_18470572, EPI_ISL_18471609, EPI_ISL_18471611, EPI_ISL_18473319, EPI_ISL_18473421, EPI_ISL_18473950, EPI_ISL_18475156, EPI_ISL_18475172, EPI_ISL_18475181, EPI_ISL_18475190, EPI_ISL_18475453`Back to Tasklist
Branch 52, now pulled under HK.3.2
Now part of HK.3.2
**Defining Mutations:** `EG.5.1.1` > `C26029A(ORF3a:Q213K)` > `G22927T(S:L455F)` **Query:** `C6541T, G22927T, C26029A, -G24944T, -A26901G` **Earliest seq:** 2023-08-16 (`EPI_ISL_18146001`, Hubei, China) **Latest seq:** 2023-09-20 (`EPI_ISL_18340137`, Illinois, USA) **Sampled Countries:** China (5: HB/3; SC; YN) USA (3: IL; NY; WA), Oman (1)Genomes:
`EPI_ISL_18146001, EPI_ISL_18246341, EPI_ISL_18290983, EPI_ISL_18292780, EPI_ISL_18313122, EPI_ISL_18322921, EPI_ISL_18330205, EPI_ISL_18333620, EPI_ISL_18340137`Back to Tasklist
Branch 53
Transferred to main repo
_transferred to cov-lineages/pango-designation#2366_ **Defining Mutations:** `EG.5.1.1` > `C27741T` > `C1912T, C1968T(ORF1a:T568I), T7111C, A20010T(ORF1b:Q2181H), T20592C, G22927C(S:L455F), C28093T(ORF8:S67F)` **Query:** `C6541T, G22927C, C27741T` **Earliest seq:** 2023-08-28 (`EPI_ISL_18345224`, Cork, Ireland) **Latest seq:** 2023-10-23 (`EPI_ISL_18471085`, Connecticut, USA) **Sampled Countries:** UK (17: EN/16; WS/1), USA (14: NY/3; NJ/2; TX/2; UT/2; AZ/1; CA/1; CT/1; MN/1; OH/1), Ireland (9), Canada (4: ON/3; BC/1), Denmark (2), France (2), China (2: SC/1; ex. Spain/1), Belgium (1), South Korea (1), Netherlands (1)Genomes:
`EPI_ISL_18250090, EPI_ISL_18284832, EPI_ISL_18290882, EPI_ISL_18290915, EPI_ISL_18308328, EPI_ISL_18308339, EPI_ISL_18315360, EPI_ISL_18321565, EPI_ISL_18332107, EPI_ISL_18332505, EPI_ISL_18345224, EPI_ISL_18354139, EPI_ISL_18362839, EPI_ISL_18362880-18362881, EPI_ISL_18362951, EPI_ISL_18375850, EPI_ISL_18377642, EPI_ISL_18385706, EPI_ISL_18385720, EPI_ISL_18385728, EPI_ISL_18385734, EPI_ISL_18388184, EPI_ISL_18388760-18388761, EPI_ISL_18389241, EPI_ISL_18398829, EPI_ISL_18399988, EPI_ISL_18400877, EPI_ISL_18403587, EPI_ISL_18403998, EPI_ISL_18407932, EPI_ISL_18416430, EPI_ISL_18416450, EPI_ISL_18420893, EPI_ISL_18420911, EPI_ISL_18422267, EPI_ISL_18427521, EPI_ISL_18429173, EPI_ISL_18429518, EPI_ISL_18430506, EPI_ISL_18433870, EPI_ISL_18438642, EPI_ISL_18442008, EPI_ISL_18443922, EPI_ISL_18448322, EPI_ISL_18452961, EPI_ISL_18456955, EPI_ISL_18467439, EPI_ISL_18467445, EPI_ISL_18467479, EPI_ISL_18471085, EPI_ISL_18475314`Back to Tasklist
Branch 54:
Defining Mutations:
EG.5.1.1
>G24368T(S:D936Y)
>G22927T(S:L455F)
Query:G13627A, G22927T, G24368T, -G3567A, -C4012T, -C5031T, -T13234C, -C17976T
Earliest seq: 2023-09-11 (EPI_ISL_18312655
, South Korea) Latest seq: 2023-11-24 (EPI_ISL_18567787
, Veneto, Italy) Sampled Countries: Finland (15), South Korea (15), USA (9: NY/7; UT/2), Italy (2), Singapore (2), Australia (1: QLD), Germany (1)Genomes:
`EPI_ISL_18312655, EPI_ISL_18343453, EPI_ISL_18347772, EPI_ISL_18347778, EPI_ISL_18347783, EPI_ISL_18347794, EPI_ISL_18347862, EPI_ISL_18354114, EPI_ISL_18394470, EPI_ISL_18408694, EPI_ISL_18411981, EPI_ISL_18411986, EPI_ISL_18412002, EPI_ISL_18412024, EPI_ISL_18412052, EPI_ISL_18412131, EPI_ISL_18439287, EPI_ISL_18439475, EPI_ISL_18445086, EPI_ISL_18445161, EPI_ISL_18449963, EPI_ISL_18458264, EPI_ISL_18458329, EPI_ISL_18460569, EPI_ISL_18502041, EPI_ISL_18503589, EPI_ISL_18511443, EPI_ISL_18533418, EPI_ISL_18533465, EPI_ISL_18533560, EPI_ISL_18533727, EPI_ISL_18534149, EPI_ISL_18539237, EPI_ISL_18539435, EPI_ISL_18539679, EPI_ISL_18539701, EPI_ISL_18539776, EPI_ISL_18541395, EPI_ISL_18541532, EPI_ISL_18544389, EPI_ISL_18547900, EPI_ISL_18554927, EPI_ISL_18555070, EPI_ISL_18564736, EPI_ISL_18567787`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_28b3b_c482d0.json?label=id:node_3526683
Back to Tasklist
Branch 55
Designated with 2 levesl: HK.24 and HK.24.1
Designated as [HK.24](https://github.com/cov-lineages/pango-designation/commit/211018361b201eda9d492fdb25dc7fbcad217804) and [HK.24.1](https://github.com/cov-lineages/pango-designation/commit/77596389b8d6291450be40a5b8a7c1701c9e5309) **Defining Mutations:** `EG.5.1.1` > `G23522A(S:E654K)` > `G22927T(S:L455F)` **Query:** `C6541T, G22927T, G23522A` **Earliest seq:** 2023-08-26 (`EPI_ISL_18284795`, Shanghai, China) **Latest seq:** 2023-09-24 (`EPI_ISL_18346833`, South Australia, Australia) **Sampled Countries:** Australia (6: QLD/2; WA/2; NSW; SA), China (3: SH), New Zealand (1)Genomes:
`EPI_ISL_18284795, EPI_ISL_18284982, EPI_ISL_18324864, EPI_ISL_18346833, EPI_ISL_18347678, EPI_ISL_18352382, EPI_ISL_18352389, EPI_ISL_18352581, EPI_ISL_18354460, EPI_ISL_18360253`Back to Tasklist
Branch 56
Defining Mutations:
EG.5.1.1
>A22582G(S:E340)
>G22927T(S:L455F)
Query:G13627A, A22582G, G22927T, -G3153A
Earliest seq: 2023-08-30 (EPI_ISL_18303241
, Portugal) Latest seq: 2023-09-25 (EPI_ISL_18355054
, Singapore) Sampled Countries: Portugal (2), Singapore (2), China (1: QH), UK (1: EN)Genomes:
`EPI_ISL_18268272, EPI_ISL_18274005, EPI_ISL_18303241, EPI_ISL_18303432, EPI_ISL_18307200, EPI_ISL_18355054`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_61cc_2ffcf0.json?label=id:node_3450332
Back to Tasklist
Branch 57
Defining Mutations:
EG.5.1.1
>A22582G(S:E340)
>G3153A(ORF1a:G963D)
>G22927T(S:L455F)
Query:G3153A, A22582G, G22927T
Earliest seq: 2023-08-14 (EPI_ISL_18146012
, Hubei, China) Latest seq: 2023-09-26 (EPI_ISL_18350530
, Basque, Spain) Sampled Countries: China (4: FJ; HB; HK; SH), Japan (2), South Korea (2), USA (2: ex. Greece), Spain (1)Genomes:
`EPI_ISL_18146012, EPI_ISL_18277143, EPI_ISL_18293356, EPI_ISL_18306220, EPI_ISL_18306632, EPI_ISL_18306769, EPI_ISL_18309318, EPI_ISL_18309324, EPI_ISL_18350530, EPI_ISL_18354289, EPI_ISL_18360277`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_61cc_2ffcf0.json?label=id:node_3450116
Back to Tasklist
Branch 58, formerly singlet, thanks to @aviczhl2 for updated info
Defining Mutations:
EG.5.1
>T26972C
>C28909T
>C2106A(ORF1a:T614N), G28423T(ORF9b:R47L)
>A21759G(S:H66R), G22927T(S:L455F), G24004A(S:K814), C25572T
Query:A18492G, G22927T, C28909T
Earliest seq: 2023-08-21 (EPI_ISL_18271704
, S. Korea) Latest seq: 2023-09-19 (EPI_ISL_18355498
, S. Korea) Sampled Countries: South Korea (6)Genomes:
`EPI_ISL_18271704, EPI_ISL_18354058, EPI_ISL_18354072, EPI_ISL_18354264, EPI_ISL_18355236, EPI_ISL_18355498`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_26418_30eca0.json?label=id:node_3429102
Back to Tasklist
Branch 59: ⚠️ careful with potential dropout/misplacement.
Defining Mutations:
EG.5.1.1
>G20134T(ORF1b:V2223L)
>G22927T(S:L455F)
Query:G13627A, G20134T, G22927T
Earliest seq: 2023-09-04 (EPI_ISL_18300595
, New South Wales) Latest seq: 2023-10-03 (EPI_ISL_18361370
, NSW) Sampled Countries: Australia (17: NSW/16; QLD)Genomes:
`EPI_ISL_18300595, EPI_ISL_18300598, EPI_ISL_18300624, EPI_ISL_18300634, EPI_ISL_18300676-18300679, EPI_ISL_18300732, EPI_ISL_18300745-18300746, EPI_ISL_18300790, EPI_ISL_18324806, EPI_ISL_18352578, EPI_ISL_18361360-18361361, EPI_ISL_18361370`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_4fa9_6ad320.json?label=id:node_3451611
Trivia:
Heilongjiang/HLJCDC-2004/2023|EPI_ISL_18245889|2023-07-25
, please check potential HK.3-dropout/misplacement.Back to Tasklist
Branch 60: Formerly
Y144F
artifact branch now maskedDefining Mutations:
EG.5.1.1
>T16545G
>C1471T, G22927T(S:L455F)
Query:G13627A, T16545G, G22927T
Earliest seq: 2023-08-25 (EPI_ISL_18228384
, Finland) Latest seq: 2023-10-04 (EPI_ISL_18362018
, Singapore) Sampled Countries: Singapore (7), China (3: SH/2; HB), Finland (1)Genomes:
`EPI_ISL_18228384, EPI_ISL_18243407, EPI_ISL_18254180, EPI_ISL_18306951, EPI_ISL_18320869, EPI_ISL_18360325, EPI_ISL_18361717, EPI_ISL_18361964, EPI_ISL_18362005, EPI_ISL_18362018, EPI_ISL_18362077`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_108b5_6b1720.json?f_userOrOld=uploaded%20sample&label=id:node_3457632
Trivia:
Y144F
artifact sub-branch now seems masked, thanks to @FedeGueli for the quick analysis and query.Back to Tasklist
Branch 61
⚠️ Please check potential reversion/artifact/misplacement,
C26681T
is quite homoplastic in HK.3*, no longer trackingpotential HK.3 dropout
**Defining Mutations:** `EG.5.1.1` > `C26681T` > `T5327C, C5986T, T22032C(S:F157S), G22927T(S:L455F)` **Query:** `T22032C, G22927T, C26681T` **Earliest seq:** 2023-09-03 (`EPI_ISL_18376557`, Sichuan) **Latest seq:** 2023-09-11 (`EPI_ISL_18376558`, Sichuan, _OR_ `EPI_ISL_18277141`, Fujian) **Sampled Countries:** China (5: SC/4; FJ)Genomes:
`EPI_ISL_18277141, EPI_ISL_18376556-18376559`Back to Tasklist
Branch 62: With a sub-branch of FLippeR
Defining Mutations:
EG.5.1.1
>C18559T(ORF1b:L1698F)
>T15927C, G22927T(S:L455F)
Query:C6541T, C18559T, G22927T
Earliest seq: 2023-08-31 (EPI_ISL_18285056
, Sichuan, China) Latest seq: 2023-09-20 (EPI_ISL_18382134
, South Korea) Sampled Countries: China (4: SC/2; SH/2), South Korea (1)Genomes:
`EPI_ISL_18285056-18285057, EPI_ISL_18320863, EPI_ISL_18360320, EPI_ISL_18382134`UShER: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_24de1_9159b0.json?label=id:node_3445922
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Branch 63
⚠️ Please check potential misplacement
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2400_ **Defining Mutations:** `EG.5.1.1` > `T14034C` > `T6556C` > `G22927T(S:L455F)` **Query:** `T6556C, T14034C, G22927T` **Earliest seq:** 2023-08-28 (`EPI_ISL_18236022`, Chiba, Japan) **Latest seq:** 2023-11-16 (`EPI_ISL_18568493`, Ardèche, France) **Sampled Countries:** South Korea (66), Japan (11), France (7), China (2: Taiwan), Singapore (2), Germany (1), Ireland (1), UK (1: England)Genomes:
`EPI_ISL_18236022, EPI_ISL_18307101, EPI_ISL_18307183, EPI_ISL_18312967, EPI_ISL_18354179, EPI_ISL_18354386, EPI_ISL_18371409, EPI_ISL_18371437, EPI_ISL_18376385, EPI_ISL_18381917, EPI_ISL_18382077, EPI_ISL_18382170, EPI_ISL_18382306, EPI_ISL_18382313, EPI_ISL_18384744, EPI_ISL_18390972, EPI_ISL_18408733, EPI_ISL_18408999, EPI_ISL_18409046, EPI_ISL_18409110, EPI_ISL_18418096, EPI_ISL_18418099, EPI_ISL_18420466, EPI_ISL_18423347, EPI_ISL_18438958, EPI_ISL_18439063, EPI_ISL_18439157, EPI_ISL_18439221, EPI_ISL_18439371, EPI_ISL_18460530, EPI_ISL_18460541, EPI_ISL_18460589, EPI_ISL_18460966, EPI_ISL_18460978, EPI_ISL_18461033, EPI_ISL_18461094, EPI_ISL_18461485, EPI_ISL_18465933, EPI_ISL_18468665, EPI_ISL_18486472, EPI_ISL_18491815, EPI_ISL_18496187, EPI_ISL_18501996, EPI_ISL_18502046, EPI_ISL_18502053, EPI_ISL_18502059, EPI_ISL_18503696, EPI_ISL_18503846, EPI_ISL_18510036, EPI_ISL_18510038, EPI_ISL_18511034, EPI_ISL_18511095, EPI_ISL_18511104, EPI_ISL_18511108, EPI_ISL_18511172, EPI_ISL_18511241, EPI_ISL_18511380, EPI_ISL_18511416, EPI_ISL_18511461, EPI_ISL_18511469, EPI_ISL_18511480, EPI_ISL_18511508, EPI_ISL_18511521, EPI_ISL_18511532, EPI_ISL_18511557, EPI_ISL_18511580, EPI_ISL_18511661, EPI_ISL_18511670, EPI_ISL_18535606, EPI_ISL_18535663, EPI_ISL_18535697, EPI_ISL_18539307, EPI_ISL_18539369, EPI_ISL_18539422, EPI_ISL_18539428, EPI_ISL_18539447, EPI_ISL_18539483, EPI_ISL_18539547, EPI_ISL_18545014, EPI_ISL_18564392, EPI_ISL_18564436, EPI_ISL_18564462-18564463, EPI_ISL_18564564, EPI_ISL_18564669, EPI_ISL_18564752, EPI_ISL_18564926, EPI_ISL_18565014, EPI_ISL_18565195, EPI_ISL_18568493, EPI_ISL_18570360`Back to Tasklist
Branch 64
Defining Mutations:
EG.5.1.6
>C28236T(ORF8:R115C)
>C16092T
>C10969T
>G526T(ORF1a:E87D)
>C23380T(S:N606)
>A12485G(ORF1a:I4074V)
>T877C, A15270T(ORF1b:E601D), G22927T(S:L455F)
Query:G526T, A15270T, G22927T
Earliest seq: 2023-10-08 (EPI_ISL_18404805
, New Brunswick, Canada) Latest seq: 2023-10-15 (EPI_ISL_18427247
, Ontario, Canada) Sampled Countries: Canada (4: ON/3; NB)Genomes:
`EPI_ISL_18404805, EPI_ISL_18426514, EPI_ISL_18426586, EPI_ISL_18427247`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_21e1_9e19a0.json?label=id:node_3437762
Back to Tasklist
Branch 65
Defining Mutations:
EG.5.1
>A3210G(ORF1a:D982G)
>G26888A
>G26227T(_TRS of Envelope_), C28720T(_TRS of ORF9c_)
>T8909C
>G22927T(S:L455F)
Query:A3210G, T8909C, G22927T
Earliest seq: 2023-09-07 (EPI_ISL_18419405
, Sicily, Italy) Latest seq: 2023-09-18 (EPI_ISL_18329969
, Denmark) Sampled Countries: Italy (13), Denmark (1)Genomes:
`EPI_ISL_18258788-18258789, EPI_ISL_18329969, EPI_ISL_18419405, EPI_ISL_18419417, EPI_ISL_18419442, EPI_ISL_18419446, EPI_ISL_18419449, EPI_ISL_18419451, EPI_ISL_18419459, EPI_ISL_18419472, EPI_ISL_18419474, EPI_ISL_18419478, EPI_ISL_18419484`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3b9a_9e23b0.json?label=id:node_3428133
Back to Tasklist
Branch 66
Defining Mutations:
EG.5.1.1
>C11779T
>C12525T(ORF1a:T4087I)
>G22927T(S:L455F)
Query:C11779T, C12525T, G22927T
Earliest seq: 2023-08-27 (EPI_ISL_18360191
, England) Latest seq: 2023-10-09 (EPI_ISL_18421921
, Belgium) Sampled Countries: South Korea (4), Canada (3: BC), Belgium (1), China (1: SH), New Zealand (1), Singapore (1), UK (1: EN)Genomes:
`EPI_ISL_18227053, EPI_ISL_18292157, EPI_ISL_18355538, EPI_ISL_18360191, EPI_ISL_18381927, EPI_ISL_18382266, EPI_ISL_18397328, EPI_ISL_18408737, EPI_ISL_18421921, EPI_ISL_18430928, EPI_ISL_18431490, EPI_ISL_18431860`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_34aaf_9ea630.json?label=id:node_3493682
Back to Tasklist
Branch 67
Defining Mutations:
EG.5.1.1
>C25613T(ORF3a:S74F)
>G22927C(S:L455F)
Query:C6541T, G22927C, C25613T, -C26681T, -G26840A
Earliest seq: 2023-10-12 (EPI_ISL_18428810
, Singapore) Latest seq: 2023-10-16 (EPI_ISL_18428772
, Singapore) Sampled Countries: Singapore (5)Genomes:
`EPI_ISL_18428766, EPI_ISL_18428769, EPI_ISL_18428771-18428772, EPI_ISL_18428810`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_41fd2_a0fe0.json?label=id:node_3487648
Back to Tasklist
Branch 68
Defining Mutations:
EG.5.1.1
>G16710A
>G22927T(S:L455F)
Query:G16710A, G13627A, G22927T, -G28904T
Earliest seq: 2023-09-25 (EPI_ISL_18355035
, Singapore) Latest seq: 2023-10-18 (EPI_ISL_18428623
, Singapore) Sampled Countries: Singapore (11)Genomes:
`EPI_ISL_18355035, EPI_ISL_18361806, EPI_ISL_18361914, EPI_ISL_18361935, EPI_ISL_18362103, EPI_ISL_18397258, EPI_ISL_18397453, EPI_ISL_18428554, EPI_ISL_18428623, EPI_ISL_18428638, EPI_ISL_18428659`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_c933_9f2590.json?label=id:node_3474466
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Branch 69
Defining Mutations:
EG.5.1.1
>G1085T(ORF1a:V274L)
>G1535A(ORF1a:V424I), G22927T(S:L455F)
Query:G1085T, G13627A, G22927T, -A11000G, -C29375T
, Earliest seq: 2023-10-02 (EPI_ISL_18361916
, Singapore) Latest seq: 2023-10-16 (EPI_ISL_18428661
, Singapore) Sampled Countries: Singapore (5)Genomes:
`EPI_ISL_18361916, EPI_ISL_18397376, EPI_ISL_18397599, EPI_ISL_18428562, EPI_ISL_18428661`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_18f8d_9f5e00.json?label=id:node_3486178
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Branch 70
Defining Mutations:
EG.5.1.1
>T21748C(S:V62)
>A16225G(ORF1b:T920A), T25036C
>G22927C(S:L455F)
Query:A16225G, T21748C, G22927C
Earliest seq: 2023-08-10 (EPI_ISL_18438105
, Beijing, China) Latest seq: 2023-10-09 (EPI_ISL_18426675
, Montana, USA) Sampled Countries: China (13: BJ/11; HB/1; HL/1), Netherlands (2), Singapore (1), USA (1: MT)Genomes:
`EPI_ISL_18254239, EPI_ISL_18331365, EPI_ISL_18362093, EPI_ISL_18384410, EPI_ISL_18386767, EPI_ISL_18426675, EPI_ISL_18438074-18438075, EPI_ISL_18438082, EPI_ISL_18438103, EPI_ISL_18438105, EPI_ISL_18438108, EPI_ISL_18438114, EPI_ISL_18438136, EPI_ISL_18438177-18438178, EPI_ISL_18438235`UShER: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_4eb1c_b77620.json?label=id:node_3464035
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Branch 71
Defining Mutations:
EG.5.1.1
>C6638T(ORF1a:H2125Y)
>G22927T(S:L455F)
Query:C6638T, G13627A, G22927T, -C14889T
Earliest seq: 2023-09-11 (EPI_ISL_18313157
, Hubei, China) Latest seq: 2023-10-09 (EPI_ISL_18438431
, Hubei, China) Sampled Countries: China (5: HB), South Korea (1)Genomes:
`EPI_ISL_18313157-18313158, EPI_ISL_18382135, EPI_ISL_18438389, EPI_ISL_18438415, EPI_ISL_18438431`UShER: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_b5b8_b7aee0.json?f_userOrOld=uploaded%20sample&label=id:node_3482675
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Branch 72
Defining Mutations:
EG.5.1.1
>C11779T
>G10261A
>C9611T(ORF1a:L3116F), C18348T
>G22927T(S:L455F)
Query:C9611T, C11779T, G22927T
Earliest seq: 2023-09-06 (EPI_ISL_18313115
, Hubei, China) Latest seq: 2023-10-09 (EPI_ISL_18406324
, Vienna, Austria) Sampled Countries: South Korea (6), Singapore (2), Austria (1), China (1: HB)Genomes:
`EPI_ISL_18313115, EPI_ISL_18355007, EPI_ISL_18355538, EPI_ISL_18376812, EPI_ISL_18381927, EPI_ISL_18382266, EPI_ISL_18406324, EPI_ISL_18408737, EPI_ISL_18435658, EPI_ISL_18439298`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3b3db_cbcfb0.json?label=id:node_3497922
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Branch 73
Defining Mutations:
EG.5.1.1
>C19170T
>G22927T(S:L455F)
Query:G13627A, C19170T, G22927T, -C1909T, -C3736T, -C5031T, -C7504T, -A18153G
Earliest seq: 2023-08-31 (EPI_ISL_18438072
, Beijing) Latest seq: 2023-10-14 (EPI_ISL_18442753
, Sichuan) Sampled Countries: China (6: SC/3; BJ/1; HB/1; SC/1), South Korea (1)Genomes:
`EPI_ISL_18320875, EPI_ISL_18360251, EPI_ISL_18360272, EPI_ISL_18438072, EPI_ISL_18438352, EPI_ISL_18439041, EPI_ISL_18442753`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_26c5d_cced10.json?label=id:node_3466266
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Branch 74
Defining Mutations:
EG.5.1.3
>A28032G(ORF8:I47V)
>A1047C(ORF1a:K261T)
>C3608A(ORF1a:L1115I), C18261T, G22927T(S:L455F)
Query:A1047C, C1889T, G22927T
Earliest seq: 2023-09-11 (EPI_ISL_18314192
, France) Latest seq: 2023-10-12 (EPI_ISL_18441710
, Netherlands) Sampled Countries: Belgium (2), France (2), Netherlands (1)Genomes:
`EPI_ISL_18314192, EPI_ISL_18337916, EPI_ISL_18338399, EPI_ISL_18399343, EPI_ISL_18441710`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_38cb6_cd6010.json?f_userOrOld=uploaded%20sample&label=id:node_3458506
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Branch 75
Defining Mutations:
EG.5.1.1
>C29253T(N:S327L)
>G22927T(S:L455F)
Query:G13627A, G22927T, C29253T, -G1067T, -C2110T, -A2730C
Earliest seq: 2023-08-17 (EPI_ISL_18389043
, Xinjiang, China) Latest seq: 2023-10-24 (EPI_ISL_18445150
, Singapore, travel history: Malaysia) Sampled Countries: Denmark (3), China (2: XJ), Singapore (2)Genomes:
`EPI_ISL_18320957, EPI_ISL_18377581, EPI_ISL_18377610, EPI_ISL_18389043, EPI_ISL_18397195, EPI_ISL_18442952, EPI_ISL_18445150`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1c2e8_a8650.json?label=id:node_3492354
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Branch 76
Defining Mutations:
EG.5.1.1
>T26609C
>C5907T(ORF1a:T1881I), T17454A
>G22927T(S:L455F)
Query:G13627A, T17454A, G22927T
Earliest seq: 2023-09-20 (EPI_ISL_18445852
, Castilla y León, Spain) Latest seq: 2023-10-13 (EPI_ISL_18402965
, Donostia-San Sebastián, Spain) Sampled Countries: Spain (9)Genomes:
`EPI_ISL_18402961, EPI_ISL_18402965, EPI_ISL_18419672, EPI_ISL_18421286, EPI_ISL_18445852, EPI_ISL_18445906, EPI_ISL_18445934, EPI_ISL_18446071-18446072`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3b023_af570.json?label=id:node_3474073
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Branch 77
Transferred to main repo
_Transferred to cov-lineages/pango-designation#2401_ **Defining Mutations:** `EG.5.1.6` > `C925T, C27161T` > `C14919A` > `G14559A` > `G22927T(S:L455F)` **Query:** `C5835T, G14559A, G22927T` **Earliest seq:** 2023-09-11 (`EPI_ISL_18381025`, British Columbia, Canada) **Latest seq:** 2023-11-21 (`EPI_ISL_18572342`, Israel) **Sampled Countries:** Canada (59: AB/25; BC/25; SK/7; ON/1; QC/1), Israel (5), USA (3: NY/2; CA), Finland (2), Sweden (2), Austria (1), Ireland (1), UK (1: EN)Genomes:
`EPI_ISL_18313726, EPI_ISL_18374552, EPI_ISL_18381025, EPI_ISL_18381642, EPI_ISL_18399548, EPI_ISL_18405416, EPI_ISL_18429724, EPI_ISL_18431316, EPI_ISL_18431484, EPI_ISL_18431577, EPI_ISL_18448820, EPI_ISL_18449315, EPI_ISL_18451058, EPI_ISL_18452675, EPI_ISL_18453011, EPI_ISL_18453157, EPI_ISL_18456002, EPI_ISL_18456201, EPI_ISL_18493062, EPI_ISL_18499142, EPI_ISL_18501414, EPI_ISL_18501469, EPI_ISL_18501539, EPI_ISL_18501675, EPI_ISL_18512520, EPI_ISL_18512575, EPI_ISL_18512726, EPI_ISL_18512904, EPI_ISL_18512975, EPI_ISL_18513012, EPI_ISL_18516832, EPI_ISL_18516837, EPI_ISL_18517029, EPI_ISL_18517372, EPI_ISL_18517374-18517375, EPI_ISL_18517477, EPI_ISL_18517505, EPI_ISL_18526773, EPI_ISL_18526937-18526938, EPI_ISL_18526942, EPI_ISL_18526999, EPI_ISL_18527195, EPI_ISL_18532450-18532451, EPI_ISL_18533407, EPI_ISL_18538515, EPI_ISL_18538528, EPI_ISL_18538535, EPI_ISL_18538740, EPI_ISL_18538774, EPI_ISL_18538986, EPI_ISL_18541507-18541508, EPI_ISL_18547665, EPI_ISL_18552699, EPI_ISL_18553923, EPI_ISL_18553948, EPI_ISL_18558921, EPI_ISL_18560813, EPI_ISL_18563933, EPI_ISL_18563975, EPI_ISL_18563992, EPI_ISL_18564064, EPI_ISL_18564086, EPI_ISL_18564088, EPI_ISL_18564119, EPI_ISL_18564154, EPI_ISL_18564182, EPI_ISL_18564194, EPI_ISL_18572342, EPI_ISL_18572380, EPI_ISL_18572384`Back to Tasklist
Branch 78
Defining Mutations:
EG.5.1.1
>C18395T(ORF1b:A1643V)
>G22927T(S:L455F)
Query:C6541T, C18395T, G22927T
Earliest seq: 2023-08-16 (EPI_ISL_18146006
, Hubei, China) Latest seq: 2023-10-15 (EPI_ISL_18453170
, British Columbia, Canada) Sampled Countries: Canada (7: BC), China (6: FJ/3; HB/2; GS/1), Japan (2)Genomes:
`EPI_ISL_18146006, EPI_ISL_18330196, EPI_ISL_18330296, EPI_ISL_18330311, EPI_ISL_18376315, EPI_ISL_18405472, EPI_ISL_18409239, EPI_ISL_18425055, EPI_ISL_18452695, EPI_ISL_18452923, EPI_ISL_18452979, EPI_ISL_18453059, EPI_ISL_18453168, EPI_ISL_18453170, EPI_ISL_18454186`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3e744_1f9880.json?label=id:node_3476703
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Branch 79
Defining Mutations:
EG.5.1.1
>T6736C
>T23287C(S:A575)
>C22075T(S:V171)
>C8389T, A16668G, C17474T(ORF1b:T1336I), G22927T(S:L455F), G26416T(E:V58F)
Query:T6736C, G13627A, G22927T
Earliest seq: 2023-08-17 (EPI_ISL_18241549
, Yunnan) Latest seq: 2023-10-14 (EPI_ISL_18454380
, Yunnan) Sampled Countries: China (12: YN)Genomes:
`EPI_ISL_18241549, EPI_ISL_18384462, EPI_ISL_18384468, EPI_ISL_18384485, EPI_ISL_18384488, EPI_ISL_18384501, EPI_ISL_18384510, EPI_ISL_18384514, EPI_ISL_18384522, EPI_ISL_18454363, EPI_ISL_18454380, EPI_ISL_18454383`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_6626_1fc330.json?label=id:node_3476751
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Branch 80
Defining Mutations:
EG.5.1.1
>C8146T
>G2035A, G6373T(ORF1a:M2036I), G22927T(S:L455F)
Query:C8146T, G13627A, G22927T, -C27557T
Earliest seq: 2023-08-28 (EPI_ISL_18289791
, Anhui, China) Latest seq: 2023-10-07 (EPI_ISL_18454332
, Yunnan, China) Sampled Countries: South Korea (6), China (3: AH, HB, YN)Genomes:
`EPI_ISL_18289791, EPI_ISL_18376503, EPI_ISL_18382123, EPI_ISL_18454332, EPI_ISL_18460781, EPI_ISL_18460783, EPI_ISL_18460821-18460822, EPI_ISL_18460834`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1d9d0_762270.json?label=id:node_3494057
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Branch 81
Defining Mutations:
EG.5.1.1
>C2857T
>G22927T(S:L455F)
Query:C2857T, G13627A, G22927T, -C5031T, -T17475C
Earliest seq: 2023-09-14 (EPI_ISL_18388886
, Hubei, China) Latest seq: 2023-10-13 (EPI_ISL_18461038
, South Korea) Sampled Countries: China (7: TW/5; HB; SC), Belgium (1), Japan (1), South Korea (1)Genomes:
`EPI_ISL_18388886, EPI_ISL_18399792, EPI_ISL_18427833, EPI_ISL_18432501, EPI_ISL_18438519, EPI_ISL_18440359, EPI_ISL_18440668, EPI_ISL_18461038, EPI_ISL_18461507, EPI_ISL_18461514`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_5f66_766bb0.json?label=id:node_3485431
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Branch 82
Defining Mutations:
EG.5.1.1
>T16494C, T22307C
>G22927C(S:L455F)
Query:G13627A, T16494C, G22927C
Earliest seq: 2023-09-12 (EPI_ISL_18376962
, Singapore, Travel History: Malaysia) Latest seq: 2023-10-09 (EPI_ISL_18461687
, New South Wales, Australia) Sampled Countries: Singapore (7), China (2: HL), Australia (1: NSW)Genomes:
`EPI_ISL_18355070, EPI_ISL_18355078, EPI_ISL_18355084, EPI_ISL_18355119, EPI_ISL_18376962, EPI_ISL_18397262, EPI_ISL_18397335, EPI_ISL_18461687, EPI_ISL_18465032, EPI_ISL_18465036`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice14_genome_1351a_73edc0.json?label=id:node_3508527
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Branch 83
Defining Mutations:
EG.5.1.1
>C29358T(N:T362I)
>T23803C(S:T747T)
>C842T(ORF1a:P193S), C15141T, T16743C, C22450T(S:L296L), G22927T(S:L455F), C24442T(S:N960N), C25916T(ORF3a:T175I), C28232T
Query:G22927T, T23803C, C29358T
Earliest seq: 2023-09-11 (EPI_ISL_18384535
, Yunnan, China) Latest seq: 2023-10-31 (EPI_ISL_18473684
, Singapore) Sampled Countries: Singapore (11), France (2), Australia (1: NSW), Canada (1: ON), China (1: YN), Germany (1)Genomes:
`EPI_ISL_18327437, EPI_ISL_18384535, EPI_ISL_18423274, EPI_ISL_18428663, EPI_ISL_18455125, EPI_ISL_18461961, EPI_ISL_18472175, EPI_ISL_18473491, EPI_ISL_18473552, EPI_ISL_18473557, EPI_ISL_18473565, EPI_ISL_18473584, EPI_ISL_18473600, EPI_ISL_18473608, EPI_ISL_18473617, EPI_ISL_18473635, EPI_ISL_18473684`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_33d1_b55240.json?label=id:node_3483621
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Branch 84
Defining Mutations:
HK.19
>C2455T
>G22927T(S:L455F), C23533T(S:N657)
Query:C2455T, C22033A, G22927T, -G25606A
Earliest seq: 2023-09-20 (EPI_ISL_18327665
,SEA
airport, travel history: China) Latest seq: 2023-10-06 (EPI_ISL_18454355
, Yunnan China) Sampled Countries: China (7)Genomes:
`EPI_ISL_18327626, EPI_ISL_18327665, EPI_ISL_18454355, EPI_ISL_18475173-18475174, EPI_ISL_18481030, EPI_ISL_18481032`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice2_genome_14b93_98620.json?label=id:node_3515333
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Branch 85: Mostly with
ORF6:N34K/C27303A
Defining Mutations:
EG.5.1.1
>C7390T
>G22927T(S:L455F)
Query:C7390T, G13627A, G22927T
Earliest seq: 2023-08-31 (EPI_ISL_18312335
, South Korea) Latest seq: 2023-10-30 (EPI_ISL_18494555
, Denmark) Sampled Countries: China (7: SC/3; HB/2; XJ/2), South Korea (4), Australia (2), Denmark (1), Spain (1)Genomes:
`EPI_ISL_18284798, EPI_ISL_18312335, EPI_ISL_18312767, EPI_ISL_18313150, EPI_ISL_18330217, EPI_ISL_18355417, EPI_ISL_18361365, EPI_ISL_18376681, EPI_ISL_18402975, EPI_ISL_18447796, EPI_ISL_18461975, EPI_ISL_18475119, EPI_ISL_18481228, EPI_ISL_18494555, EPI_ISL_18495106`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_25e0e_b6750.json?label=id:node_3492892
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Branch 86: many with
S:N17T/A21612C
Defining Mutations:
EG.5.1.1
>G25855T(ORF3a:D155Y)
>G22927T(S:L455F)
Query:A21612C, G22927T, G25855T
Earliest seq: 2023-08-31 (EPI_ISL_18284769
, Sichuan, China) Latest seq: 2023-10-24 (EPI_ISL_18458002
, Kuala Lumpur, Malaysia) Sampled Countries: China (9: YN/6; SC/3), Malaysia (3), Japan (1)Genomes:
`EPI_ISL_18284769, EPI_ISL_18324153, EPI_ISL_18324208, EPI_ISL_18324235, EPI_ISL_18384546, EPI_ISL_18419659, EPI_ISL_18419662, EPI_ISL_18454181, EPI_ISL_18458002, EPI_ISL_18475350, EPI_ISL_18481259, EPI_ISL_18488097, EPI_ISL_18488110`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_372c6_bbb70.json?label=id:node_3488769
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Branch 87
Defining Mutations:
EG.5.1
>C15960T
>C16260T
>G22927T(S:L455F), C24771T(S:A1070V), C25658T(ORF3a:T89I)
Query:C15960T, C16260T, A18492G, G22927T
Earliest seq: 2023-09-01 (EPI_ISL_18384575
, Yunnan, China) Latest seq: 2023-10-27 (EPI_ISL_18493260
, Alberta, Canada) Sampled Countries: China (5: SH/3; SX; YN), Canada (3: AB), South Korea (2)Genomes:
`EPI_ISL_18384575, EPI_ISL_18426071, EPI_ISL_18436785, EPI_ISL_18460945-18460946, EPI_ISL_18475132, EPI_ISL_18481223, EPI_ISL_18493260, EPI_ISL_18495087, EPI_ISL_18495466`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice95_genome_43bfd_a83e0.json?label=id:node_3517572
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Branch 88
⚠️ sibling to Branch 32 please check potential misplacement
Defining Mutations:
EG.5.1.1
>T4579A
>A4576T
>G22927T(S:L455F)
Query:A4576T, G13627A, G22927T
Earliest seq: 2023-08-18 (EPI_ISL_18239385
, South Korea) Latest seq: 2023-10-30 (EPI_ISL_18520721
, Saitama, Japan) Sampled Countries: South Korea (39), Japan (2), USA (2, ex. Japan), China (1, ex. S. Korea)Genomes:
`EPI_ISL_18239385, EPI_ISL_18313064, EPI_ISL_18320761, EPI_ISL_18354110, EPI_ISL_18355244, EPI_ISL_18355256, EPI_ISL_18355270, EPI_ISL_18355539, EPI_ISL_18368435, EPI_ISL_18368571, EPI_ISL_18382929, EPI_ISL_18408987, EPI_ISL_18411143, EPI_ISL_18432570, EPI_ISL_18439431, EPI_ISL_18460891, EPI_ISL_18460981, EPI_ISL_18461196, EPI_ISL_18503870, EPI_ISL_18510989, EPI_ISL_18511173, EPI_ISL_18511218, EPI_ISL_18511236, EPI_ISL_18511259, EPI_ISL_18511379, EPI_ISL_18511388, EPI_ISL_18511531, EPI_ISL_18511534, EPI_ISL_18511636, EPI_ISL_18511644, EPI_ISL_18511659, EPI_ISL_18511666, EPI_ISL_18511675, EPI_ISL_18511683, EPI_ISL_18520721, EPI_ISL_18535535, EPI_ISL_18539100, EPI_ISL_18539189, EPI_ISL_18539430, EPI_ISL_18539531, EPI_ISL_18539554, EPI_ISL_18539681, EPI_ISL_18539751, EPI_ISL_18539824`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_2459b_3b16b0.json?f_userOrOld=uploaded%20sample&label=id:node_3488766
view from
EG.5.1.1
>T4579A
branch, sibling to Branch 32?details
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Branch 89
Defining Mutations:
EG.5.1.1
>C27406T(ORF7a:L5F)
>G22927T(S:L455F)
Query:C6541T, G13627A , G22927T, C27406T
Earliest seq:2023-08-11
(EPI_ISL_18145981
, Hubei, China) Latest seq: 2023-10-18 (EPI_ISL_18487967
, Henan, China) Sampled Countries: China (6: HA/2; HB/2; SC/2; BJ), South Korea (1)Genomes:
`EPI_ISL_18145981, EPI_ISL_18320871, EPI_ISL_18360327, EPI_ISL_18382216, EPI_ISL_18438321, EPI_ISL_18485262, EPI_ISL_18487967`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice16_genome_15d09_3ad150.json?label=id:node_3506957
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Branch 90
Defining Mutations:
EG.5.1.1
>C13724T(ORF1a:A4487V), A25636T(ORF3a:N82Y)
>T10750C, G22927T(S:L455F)
Query:G13627A, C13724T, G22927T, -C5031T
Earliest seq: 2023-08-22 (EPI_ISL_18272130
, South Korea) Latest seq: 2023-10-19 (EPI_ISL_18451971
,SEA
airport, travel history: South Korea) Sampled Countries: South Korea (6), USA (2: ex. South Korea)Genomes:
`EPI_ISL_18272130, EPI_ISL_18376686, EPI_ISL_18376765, EPI_ISL_18451971, EPI_ISL_18460748, EPI_ISL_18488908-18488909, EPI_ISL_18492194`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_42b73_3bb260.json?label=id:node_3520099
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Branch 91
Defining Mutations:
EG.5.1.1
>C22987T(S:A475A)
>G22927T(S:L455F)
>G19419A, G21974C(S:D138H)
Query:G13627A, G19419A, G21974C
Earliest seq: 2023-08-24 (EPI_ISL_18284675
, Beijing, China) Latest seq: 2023-11-04 (EPI_ISL_18486471
, Dublin, Ireland) Sampled Countries: China (6: SC/4; BJ; YN), Ireland (2), Greece (1)Genomes:
`EPI_ISL_18284675, EPI_ISL_18409255, EPI_ISL_18409302, EPI_ISL_18429520, EPI_ISL_18438109, EPI_ISL_18442759, EPI_ISL_18454352, EPI_ISL_18486471, EPI_ISL_18490986`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice2_genome_6555_3bdc60.json?label=id:node_3502929
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Branch 92
Defining Mutations:
EG.5.1.1
>C629T(ORF1a:L122F)
>A1168G
>C22987T(S:A475A)
>T595C, C20148T, G22927T(S:L455F)
Query:A1168G, G22927T, C22987T
Earliest seq: 2023-09-08 (EPI_ISL_18330247
, Hubei, China) Latest seq: 2023-10-30 (EPI_ISL_18539359
, South Korea) Sampled Countries: South Korea (5), Japan (2), China (1, HB), USA (1: CA)Genomes:
`EPI_ISL_18330247, EPI_ISL_18435755, EPI_ISL_18443954, EPI_ISL_18446528, EPI_ISL_18502023, EPI_ISL_18503555, EPI_ISL_18511230, EPI_ISL_18520709, EPI_ISL_18539359`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_6555_3bdc50.json?label=id:node_3498262
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Branch 93
Defining Mutations:
EG.5.1
>G26051T(ORF3a:S220I)
>G9269A(ORF1a:G3002S)
>T1216C, A9034G, A12121T, A12519G(ORF1a:D4085G), G22927T(S:L455F)
Query:G9269A, G22927T, G26051T
Earliest seq: 2023-10-21 (EPI_ISL_18453659
, South Australia) Latest seq: 2023-11-05 (EPI_ISL_18524643
, Queensland) Sampled Countries: Australia (7: QLD/6; SA)Genomes:
`EPI_ISL_18453659, EPI_ISL_18489126, EPI_ISL_18501702, EPI_ISL_18501758, EPI_ISL_18524643, EPI_ISL_18524655, EPI_ISL_18524668`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice52_genome_199a5_39a640.json?label=id:node_3459700
Back to Tasklist
Branch 94
a sub-branch of #1074 proposed by @aviczhl2
Defining Mutations:
EG.5.1.13
> _G670T_rev(ORF1a:R135S_rev)
_ >T28861C
>G8889A(ORF1a:R2875H)
>C13381T
>G22424T(S:A288S)
>C25047T(S:P1162L)
>G25855T(ORF3a:D155Y)
>G22927T(S:L455F)
Query:G8889A, C13381T, G22927T
Earliest seq: 2023-10-10 (EPI_ISL_18486858
, Temuco, Chile) Latest seq: 2023-11-26 (EPI_ISL_18582164
, Ontario, Canada) Sampled Countries: Canada (14: ON/13; NS), Chile (3), USA (3: NY/2; PA)Genomes:
`EPI_ISL_18483588, EPI_ISL_18483657, EPI_ISL_18486858, EPI_ISL_18523437, EPI_ISL_18534577, EPI_ISL_18548162, EPI_ISL_18581551-18581554, EPI_ISL_18581688, EPI_ISL_18581705, EPI_ISL_18582159, EPI_ISL_18582162, EPI_ISL_18582164, EPI_ISL_18582914, EPI_ISL_18582921-18582922, EPI_ISL_18582983, EPI_ISL_18602138`UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_7d45_55cdd0.json?label=id:node_3474267
Back to Tasklist
Singlets
Guangdong/GDCDC_GZ_0568/2023|EPI_ISL_18033894|2023-06-28
EG.5.1 > G1069A > C12005T > C9803T, A13707G, C14809T(ORF1b:R448C), C18348T, G22927C(S:L455F) [Query:C14809T, C18348T, G22927C
, 07/24]Japan/PG-568093/2023|EPI_ISL_18279075|2023-09-05
EG.5.1 > T15198A > C1191A(ORF1a:P309Q), A24999C(S:D1146A), A27642G > A21137G(ORF1a:K2557R) > T25851C > C6120T(ORF1a:S1952L), T13030C, G22927T(S:L455F) [Query:C1191A, T15198A, G22927T
, 09/19]Canada/QC-L00671579001/2023|EPI_ISL_18478213|2023-10-30
EG.5.1 > T15198A > G22317C(S:G252A) > C3267T(ORF1a:T1001I), T8421C(ORF1a:M2719T), G22927T(S:L455F), C22949T(S:P463S) [Query:T15198A, G22317C, G22927T
, 11/08]Sichuan/NJCDC-0906-7/2023|EPI_ISL_18261486|2023-08-30
EG.5.1.1 > A3069G(ORF1a:D935G) > C367T, A1197C(ORF1a:E311A), A6925G, G22927T(S:L455F), T27212C(ORF6:L4P) [Query:A3069G, C6541T, G22927T
, 09/14]Shanghai/SCDC-HP-XG-0731-1/2023|EPI_ISL_18138078|2023-07-31
EG.5.1.1 > G3242A(ORF1a:G993S) > G1595A(ORF1a:E444K), C6628T, G22927T(S:L455F), A27721G(ORF7a:I110V) [Query:G3242A, C6541T, G22927T
, 08/25]Shanghai/SCDC-XG09-13670/2023|EPI_ISL_18285000|2023-09-07
EG.5.1.1 > C3653T(ORF1a:L1130F) > G410T(ORF1a:G49C), C1498T, C2227A, C6395T, C11563T, G22927C(S:L455F), G27604T(ORF7a:V71L) [Query:C3653T, C6541T, G22927C
, 09/19]South_Korea/KDCA262399/2023|EPI_ISL_18271956|2023-08-22
EG.5.1.1 > C7764T(ORF1a:S2500F) > T5448C(ORF1a:V1728A), G22927T(S:L455F), C25539T [Query:C7764T, G13627A, G22927T
, 09/18]Japan/TKYnat15208/2023|EPI_ISL_18285185|2023-09-01
EG.5.1.1 > C13730T(ORF1b:A88V) > T12727C, G22927T(S:L455F) [Query:C6541T, C13730T, G22927T, -C11779T
, 09/20]Australia/QLD0x01374B/2023|EPI_ISL_18122559|2023-08-09
FLIP+346I+478R EG.5.1.1 > C16830T, C18348T, G22599T(S:R346I), G22927T(S:L455F), C22995G(S:T478R), T23176C [Query:C18348T, G22599T, G22927T
, 08/22]South_Korea/KDCA262306/2023|EPI_ISL_18271874|2023-08-15
EG.5.1.1 > C21588T(S:P9L) > G22927T(S:L455F), C28770T(N:T166I) [Query:G13627A, C21588T, G22927T
, 09/18]Anhui/HCDC-176/2023|EPI_ISL_18289771|2023-09-04
EG.5.1.1 > C24130T > G9177T(ORF1a:G2971V), T28705C > A10863C(ORF1a:E3533A), G22927T(S:L455F), G25522A(ORF3a:G44R), G27933A(ORF8:A14T) [Query:G9177T, G22927T, C24130T
, 09/20]GZSCDC-GY07-14/2023|EPI_ISL_18074217|2023-07-18
EG.5.1.1 > G24926T(S:V1122L) > C1960T, C12076T, T22926C(S:L455S), T27428A(ORF7a:L12H) [Query:G13627A, T22926C, G24926T
, 08/07]England/CLIMB-CM7YRMOM/2023|EPI_ISL_18227115|2023-08-22
EG.5.1.3 > A4340G(ORF1a:I1359V) > A2163G(ORF1a:E633G) > C23185T > T11932G, T14022C, T22926C(S:L455S) [Query:A2163G, A4340G, T22926C
, 09/06]Sweden/W-49492298L6/2023|EPI_ISL_18249322|2023-08-23
EG.5.1.3 > A10703C > C1314T(ORF1a:T350I), C9118T > G4907A(ORF1a:G1548S) > C6936G(ORF1a:S2224C), C18959T(ORF1b:A1831V), G22094T(S:D178Y), T22926C(S:L455S), G27160A(M:S213N) [Query:G4907A, C9118T, T22926C
, 09/12]Spain/CT-HUGTiP-B1R154/2023|EPI_ISL_18281164|2023-09-13
EG.5.1.3 > T14568C > T7651C, G27962T(ORF8:Q23H) > T4579A, C19017T, G22927T(S:L455F) [Query:C1889T, T7651C, G22927T
, 09/19]Canada/ON-PHL-23-30576/2023|EPI_ISL_18277805|2023-09-11
EG.5.1.4 > C26111T(ORF3a:P240L) > C21622A > C9430T > C20133T > G22927T(S:L455F) [Query:C9430T, C20133T, G22927T
, 09/18]USA/NY-URMC-N6S1J239-1/2023|EPI_ISL_18247548|2023-08-27
EG.5.1.4 > C26111T(ORF3:P240L) > G25563T(ORF3a:Q57H) > C1427T(ORF1a:H388Y) > G25494A > A21759G(S:H66R), G22927T(S:L455F) [Query:G22927T, G25494A, G25563T
, 09/11]USA/MD-HP49490-PIDPVKAURD/2023|EPI_ISL_18432449|2023
HV.1 (EG.5.1.6.1) > C2695T > C26964T(M:H148Y) > C27600T > C14376T > A5424G(ORF1a:K1720R) > C4752T(ORF1a:T1496I), G22927T(S:L455F) [Query:A5424G, C14376T, G22927T
, 10/24]USA/OH-ODH-SC3032871/2023|EPI_ISL_18422243|2023-09-29
HV.1 > A5021G(ORF1a:M1586V) > C6117T(ORF1a:A1951V), G22927T(S:L455F), C29028T(N:A252V) [Query:A5021G, C5835T, G22927T
, 10/23]Back to Tasklist
Doublets
USA/NY-NYULH-16857/2023|EPI_ISL_18440726|2023-10-19
andUSA/NY-CDC-VSX-A357619/2023|EPI_ISL_18534359|2023-10-26
EG.5.1 > C2147T(ORF1a:L628F), T6115C > G18498T(ORF1b:M1677I) > C21811T, A22911T(S:N450I), G22927T(S:L455F) [Query:C2147T, G18498T, G22927T
, 2 seqs, 11/22] (Another 3 seqs not on GISAID yetShanghai/SCDC-MH200506/2023|EPI_ISL_18114819|2023-07-30
andLiaoning/LNCDC-360-1/2023|EPI_ISL_18330279|2023-09-12
EG.5.1 > C6706T > C7482T(ORF1a:S2406L) > C2507T(ORF1a:P748S), C4543T, C8251T, G22927T(S:L455F) [Query:C6706T, C7482T, G22927T
, 2 seqs, 09/30]Shanghai/SCDC-804/2023|EPI_ISL_18268355|2023-09-02
andShanghai/SCDC-831/2023|EPI_ISL_18284896|2023-09-09
EG.5.1.1 > A3021G(ORF1a:H919R), A21493C > C1913T(ORF1a:R550C), C4965T(ORF1a:T1567I), C17977T(ORF1b:L1504F), A19237C, G22927T(S:L455F), C27393T, C28791T(N:A173V) [Query:A3021G, A21493C, G22927T
, 2 seqs, 09/19]Taiwan/CDC-W30906/2023|EPI_ISL_18164789|2023-07-29
andUSA/HI-H2324424/2023|EPI_ISL_18283168|2023-08-29
EG.5.1.1 > C6317T(ORF1a:P2018S) > C1567T, C8152T, C16192T(ORF1b:P909S), G22927C(S:L455F), G25606A(ORF3a:A72T) [Query:C6317T, C6541T, G22927C
, 2 seqs, 09/19]Sichuan/YACDC-XGcx133/2023|EPI_ISL_18232742|2023-08-14
andSichuan/YACDC-XGCX151/2023|EPI_ISL_18304270|2023-09-18
EG.5.1.1 > C6327T(ORF1a:T2021I) > C1684A, A17008G(ORF1b:I1181V), G22927C(S:L455F), G27217T(ORF6:D6Y) [Query:C6327T, C6541T, G22927C
, 2 seqs, 09/25]Hubei/HCDC-ES2799/2023|EPI_ISL_18254184|2023-08-30
andEngland/CLIMB-CM7YEDUX/2023|EPI_ISL_18274069|2023-09-08
EG.5.1.1 > C9142T > G22927T(S:L455F) [Query:C9142T, G13627A, G22927T
, 2 seqs, 09/18]Shanghai/SCDC-XG08-12942/2023|EPI_ISL_18268428|2023-08-27
andShanghai/SCDC-836/2023|EPI_ISL_18284901|2023-09-10
EG.5.1.1 > C9996T(ORF1a:S3244L) > G22927T(S:L455F) [Query:C6541T, C9996T, G22927T
, 2 seqs, 09/19]Sichuan/CDCDC-3-LZJ/2023|EPI_ISL_18166147|2023-07-29
andSichuan/CDCDC-19-CX2806/2023|EPI_ISL_18246264|2023-08-20
EG.5.1.1 > C11779T > C7420T > A12644G(ORF1a:I4127V), G16662A, G22927T(S:L455F), A27736T(ORF7a:T115S), C28585T [Query:C7420T, C11779T, G22927T
, 2 seqs, 09/11]USA/OR-OSPHL08951/2023|EPI_ISL_18285283|2023-09-07
andUSA/OR-OSPHL08953/2023|EPI_ISL_18285285|2023-09-10
EG.5.1.1 > C11956T > C17746T(ORF1b:P1427S), T20252C(ORF1b:I2262T), G22927T(S:L455F) [Query:C11956T, G13627A, G22927T
, 2 seqs, 09/20]Shanghai/SCDC-XG09-13443/2023|EPI_ISL_18284954|2023-08-30
andSichuan/MYCDC-XGCX312/2023|EPI_ISL_18284766|2023-09-03
EG.5.1.1 > C14571T > T16340C(ORF1b:I958T), T17736C, G22927T(S:L455F) [Query:C6541T, C14571T, G22927T, -A1051G
, 2 seqs, 09/19]Germany/NW-RKI-I-1137155/2023|EPI_ISL_18131003|2023-08-02
andUkraine/81521/2023|EPI_ISL_18539909|2023-10-12
EG.5.1.3 > C1059T(ORF1a:T265I) > G22927C(S:L455F) [Query:C1059T, C1889T, G22927C
, 2 seqs, 11/23]Canada/QC-L00650653001/2023|EPI_ISL_18252385|2023-08-28
andCanada/QC-L00650647001/2023|EPI_ISL_18252388|2023-08-29
EG.5.1.3 > C17718T > A17066G(ORF1b:Y1200C), A17622G, G22927T(S:L455F) [Query:C1889T, C17718T, G22927T
, 2 seqs, 09/12]Canada/ON-PHL-23-36533/2023|EPI_ISL_18448204|2023-10-18
andCanada/ON-PHL-23-36753/2023|EPI_ISL_18448385|2023-10-20
HV.1 (EG.5.1.6.1) > C12513T(ORF1a:T4083M) > T17343C > G22918T(S:R452) > T22926C(S:L455S), C29784T [Query:C12513T, T17343C, T22926C
, 2 seqs, 10/30]USA/HI-H2325918/2023|EPI_ISL_18487957|2023-10-26
andUSA/HI-H2325960/2023|EPI_ISL_18535129|2023-11-03
HV.1 > T23198C(S:L546L) > C29466T > T28417C(ORF9b:I45T) > C875T(ORF1a:L204F), G22927T(S:L455F) [Query:G22927T, T23198C, T28417C
, 2 seqs, 11/22]Back to Tasklist
Triplets
Shanghai/SCDC-770/2023|EPI_ISL_18232641|2023-08-20
;Shanghai/SCDC-802/2023|EPI_ISL_18268353|2023-08-31
andGermany/NW-RKI-I-1138223/2023|EPI_ISL_18343384|2023-09-19
EG.5.1.1 > G347A(ORF1a:V28I) > T27956C > G3091A > C13959T, T22020G(S:M153R), G22927T(S:L455F) [Query:G347A, G3091A, G22927T
, 3 seqs, 10/04]Shanghai/SCDC-0823-3241/2023|EPI_ISL_18208400|2023-08-21
;France/BRE-IPP21293/2023|EPI_ISL_18350826|2023-09-18
andUSA/CA-GBW-H20-334-1265/2023|EPI_ISL_18357649|2023-09-26
EG.5.1.1 > G347A(ORF1a:V28I) > T27956C > G22927T(S:L455F), A26117G(ORF3a:E242G) [Query:G347A, G22927T, T27956C, -G3091A
, 3 seqs, 10/06]Yunnan/YNCDC-2364/2023|EPI_ISL_18166234|2023-08-02
;Yunnan/YNCDC-2493/2023|EPI_ISL_18241493|2023-08-28
andYunnan/YNCDC-2972/2023|EPI_ISL_18384579|2023-09-22
EG.5.1.1 > C629T(ORF1a:L122F) > A1168G > T6640C > C18864T, G22927T(S:L455F), A25506G [Query:C629T, T6640C, G22927T
, 3 seqs, 10/12]Xinjiang/XJCDCWLMQ-412/2023|EPI_ISL_18161044|2023-07-29
;South_Korea/KDCA271622/2023|EPI_ISL_18511017|2023-10-20
;Shanghai/SCDC-JD1024_1/2023|EPI_ISL_18495067|2023-10-21
andDenmark/DCGC-663353/2023|EPI_ISL_18518786|2023-11-06
EG.5.1.1 > C4832T > G22927T(S:L455F) [Query:C4832T, G13627A, G22927T, C27874T
, 3 seqs, 11/18]Shanghai/SCDC-FX0906-018/2023|EPI_ISL_18284805|2023-09-03
;Hubei/HCDC-JZ3118/2023|EPI_ISL_18376469|2023-09-25
andHubei/HCDC-YC3307/2023|EPI_ISL_18438465|2023-09-27
EG.5.1.1 > C26151T > C19524G, C20235T, G22927T(S:L455F), G29044A [Query:C19524G, G22927T, C26151T
, 3 seqs, 10/26]Australia/SA708969/2023|EPI_ISL_18453685|2023-10-23
;Australia/SA832208/2023|EPI_ISL_18536619|2023-11-14
andAustralia/SA832209/2023|EPI_ISL_18536620|2023-11-14
EG.5.1.3 > C1057T > G18462A > C6578T(ORF1a:L2105F) > G22927T(S:L455F), C26058T, T27210C [Query:C1057T, C6578T, G22927T
, 3 seqs, 11/23] thanks to @FedeGueliSpain/CU-19903/2023|EPI_ISL_18294739|2023-08-22
;Denmark/DCGC-661638/2023|EPI_ISL_18442881|2023-10-16
andItaly/LOM_Unimi-3611-23/2023|EPI_ISL_18443629|2023-10-19
EG.5.1.6 > C12513T(ORF1a:T4083M) > G22927T(S:L455F) [Query:C5835T, C12513T, G22927T
, 3 seqs, 10/28]Back to Tasklist
Quadruplets
Shanghai/SCDC-826/2023|EPI_ISL_18284891|2023-09-07
;Yunnan/YNCDC-3103/2023|EPI_ISL_18454372|2023-10-13
;Sichuan/CDCDC-19-CX3446/2023|EPI_ISL_18457460|2023-10-22
andHubei/HCDC-WH3507/2023|EPI_ISL_18485337|2023-10-25
EG.5.1.1 > A2483G(ORF1a:I740V) > T15996C, G22927C(S:L455F) [Query:A2483G, G13627A, G22927C
, 4, 11/08], many withS:R158K/G22035A
andS:E554K/G23222A
South_Korea/KDCA267746/2023|EPI_ISL_18408949|2023-09-18
;South_Korea/KDCA268248/2023|EPI_ISL_18411258|2023-09-19
;South_Korea/KDCA269573/2023|EPI_ISL_18460793|2023-10-04
; andSouth_Korea/KDCA269703/2023|EPI_ISL_18460915|2023-10-09
EG.5.1.1 > C3695T > G22927T(S:L455F) [Query:C3695T, G13627A, G22927T, -T2959C
, 4 seq, 11/03]France/COR-HCL-723001296701/2023|EPI_ISL_18387770|2023-09-25
;France/NAQ-HCL723001378601/2023|EPI_ISL_18423405|2023-10-09
;Austria/AGES-1141981/2023|EPI_ISL_18485506|2023-10-18
andGermany/BY-MVP-000022265/2023|EPI_ISL_18525885|2023-10-30
EG.5.1.3 > C6151T > G2468A(ORF1a:A735T), T22926G(S:L455W) [Query:C6151T, T22926G
, 4 seqs, 11/21]Back to Tasklist
Quintuplets
Fujian/FCDC-QZ08S024/2023|EPI_ISL_18145964|2023-08-18
;England/CLIMB-CM7YJZ4C/2023|EPI_ISL_18392773|2023-10-05
;Yunnan/YNCDC-3090/2023|EPI_ISL_18454344|2023-10-12
;Yunnan/YNCDC-3139/2023|EPI_ISL_18488099|2023-10-12
;Singapore/R78MR69/2023|EPI_ISL_18444918|2023-10-25
;South_Korea/KDCA273761/2023|EPI_ISL_18535687|2023-10-31
andUSA/MN-MDH-37408/2023|EPI_ISL_18510684|2023-11-01
EG.5.1.1 > C25578T > G22927T(S:L455F) [Query:C8320T, G22927T, C25578T
, 5 seqs, 11/23]Back to Tasklist